COVID-19, renin-angiotensin system and endothelial dysfunction

R Amraei, N Rahimi - Cells, 2020 - mdpi.com
The newly emergent novel coronavirus disease 2019 (COVID-19) outbreak, which is caused
by SARS-CoV-2 virus, has posed a serious threat to global public health and caused …

Endothelial dysfunction and hypertension

D Konukoglu, H Uzun - Hypertension: from basic research to clinical …, 2017 - Springer
In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is
known to be a tissue regulating vascular tone, cell growth and the interaction between the …

[HTML][HTML] Epidemiology and immune pathogenesis of viral sepsis

GL Lin, JP McGinley, SB Drysdale… - Frontiers in …, 2018 - frontiersin.org
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …

The contribution of homocysteine metabolism disruption to endothelial dysfunction: state-of-the-art

R Esse, M Barroso, I Tavares de Almeida… - International journal of …, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the
metabolism of the essential amino acid methionine. Hcy is considered a risk factor for …

Flavonoids in hypertension: A brief review of the underlying mechanisms

D Maaliki, AA Shaito, G Pintus, A El-Yazbi… - Current opinion in …, 2019 - Elsevier
Highlights•Increased flavonoid consumption imparts antihypertensive benefits.•Luteolin,
Quercetin, Kaempferol, Epicatechin, and Daidzein increase eNOS activity.•Many flavonoids …

Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets

MG Scioli, G Storti, F D'Amico… - Journal of Clinical …, 2020 - mdpi.com
Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …

Renin-angiotensin system in pathogenesis of atherosclerosis and treatment of CVD

AV Poznyak, D Bharadwaj, G Prasad… - International Journal of …, 2021 - mdpi.com
Atherosclerosis has complex pathogenesis, which involves at least three serious aspects:
inflammation, lipid metabolism alterations, and endothelial injury. There are no effective …

[HTML][HTML] Nitric oxide bioavailability dysfunction involves in atherosclerosis

J Chen, Z Ye, X Wang, J Chang, M Yang… - Biomedicine & …, 2018 - Elsevier
The pathological characteristics of atherosclerosis (AS) include lipid accumulation, fibrosis
formation and atherosclerotic plaque produced in artery intima, which leads to vascular …

[HTML][HTML] Atrial fibrillation and coronary artery disease: an integrative review focusing on therapeutic implications of this relationship

A Batta, J Hatwal, A Batta, S Verma… - World Journal of …, 2023 - ncbi.nlm.nih.gov
The incidence of both atrial fibrillation (AF) and coronary artery disease (CAD) increases
with advancing age. They share common risk factors and very often coexist. Evidence points …

Heme oxygenase-1 and carbon monoxide in the heart: the balancing act between danger signaling and pro-survival

LE Otterbein, R Foresti, R Motterlini - Circulation research, 2016 - Am Heart Assoc
Understanding the processes governing the ability of the heart to repair and regenerate after
injury is crucial for developing translational medical solutions. New avenues of exploration …