Endothelial cell activation, injury, and dysfunction underlies the pathophysiology of vascular
diseases and infections associated with vascular dysfunction, including human …

Subarachnoid Hemorrhage (SAH) typically, occurs in patients over 55 years of age and can
cause a significant loss of productivity. SAH also has a high mortality rate and those who …

Background Burn shock caused by vascular leakage is one of the main causes of high
mortality in severe burn injury. However, the pathophysiological mechanism of vascular …

Abstract Aims Considering phycobiliproteins of Spirulina maxima has shown a wide margin
of security in pregnant and non-pregnant animals as well as antioxidant properties, present …

Gut microbiota modulates host physiology and pathophysiology through the production of
microbial metabolites. Diet is a crucial factor in shaping the microbiome, and gut microbes …

Background: Circular non-coding RNA (circRNA) has a variety of biological functions.
However, the expression profile and potential effects of circRNA on atherosclerosis (AS) and …

Reactive nitrogen species (RNS) such nitric oxide (NO) and its derivatives are a common
occurrence both in biotic and abiotic environments. In living systems, their formation is …

Endothelial dysfunction is characterized by altered vascular permeability and prothrombotic,
pro-inflammatory phenotypes. Endothelial dysfunction results in end-organ damage and has …

Endothelial dysfunction is a hallmark of a wide range of cardiovascular diseases and is often
linked to oxidative stress and inflammation. Our earlier study reported the formation of a …

Purpose At first, p53 was believed to be present primarily in malignant cells. In fact, p53
turned out to play a major role in vascular remodeling associated with transplantation …