Redox-dependent processes influence most cellular functions, such as differentiation,
proliferation, and apoptosis. Mitochondria are at the center of these processes, as …

Mitochondrial dysfunction and endoplasmic reticulum (ER) stress have been suggested to
play a key role in insulin resistance development. Reactive oxygen species (ROS) …

Metabolic syndrome comprises a cluster of cardiovascular risk factors (hypertension, altered
glucose metabolism, dyslipidemia, and abdominal obesity) that occur in obese children …

Given their essential function in aerobic metabolism, mitochondria are intuitively of interest
in regard to the pathophysiology of diabetes. Qualitative, quantitative, and functional …

Acetylation has recently emerged as an important mechanism for controlling a broad array of
proteins mediating cellular adaptation to metabolic fuels. Acetylation is governed, in part, by …

The mitochondria are involved in active and dynamic processes, such as mitochondrial
biogenesis, fission, fusion and mitophagy to maintain mitochondrial and cellular functions. In …

Mitochondria are essential for cellular bioenergetics by way of energy production in the form
of ATP through the process of oxidative phosphorylation. This crucial task is executed by five …

Despite a lack of consistent diagnostic criteria, the metabolic syndrome (MetS) is
increasingly evident in children and adolescents, portending a tsunami of chronic disease …

Diet induced obesity is associated with impaired mitochondrial function and dynamic
behavior. Mitochondria are highly dynamic organelles and the balance in fusion/fission is …

Background Mitochondria are dynamic organelles that frequently undergo fission and fusion
processes, and imbalances in these processes may be involved in obesity and insulin …