[HTML][HTML] Risk and management of bleeding complications with direct oral anticoagulants in patients with atrial fibrillation and venous thromboembolism: a narrative …

S Ballestri, E Romagnoli, D Arioli, V Coluccio… - Advances in …, 2023 - Springer
Atrial fibrillation (AF) and venous thromboembolism (VTE) are highly prevalent conditions
with a significant healthcare burden, and represent the main indications for anticoagulation …

Systematic review of efficacy of direct oral anticoagulants and vitamin K antagonists in left ventricular thrombus

L Huang, Y Tan, Y Pan - ESC Heart Failure, 2022 - Wiley Online Library
Aims Left ventricular thrombus (LVT) increases the risk of thrombotic events and mortality.
Vitamin K antagonists (VKAs) used to treat LVT have several known risks, as a result of …

[HTML][HTML] Long-term comparative effectiveness and safety of dabigatran, rivaroxaban, apixaban and edoxaban in patients with atrial fibrillation: A nationwide cohort …

M Grymonprez, TL De Backer, X Bertels… - Frontiers in …, 2023 - frontiersin.org
Background: Although non-vitamin K antagonist oral anticoagulants (NOACs) are
recommended over vitamin K antagonists (VKAs) in atrial fibrillation (AF) management …

[HTML][HTML] The introduction of direct oral anticoagulants has not resolved treatment gaps for frail patients with nonvalvular atrial fibrillation

M Orlandi, DC Dover, RK Sandhu, NM Hawkins… - Canadian Journal of …, 2022 - Elsevier
Background The extent to which the introduction of direct oral anticoagulants (DOACs)
influenced treatment patterns in frail and nonfrail patients with nonvalvular atrial fibrillation …

Current and potentially novel antithrombotic treatment in acute ischemic stroke

A Ceulemans, HMH Spronk, H Ten Cate… - Thrombosis …, 2024 - Elsevier
Acute ischemic stroke (AIS) is the most common type of stroke and requires immediate
reperfusion. Current acute reperfusion therapies comprise the administration of intravenous …

[HTML][HTML] Percutaneous Left Atrial Appendage Occlusion—Current Evidence and Future Directions

J Rotta detto Loria, S Desch, J Pöss, K Kirsch… - Journal of Clinical …, 2023 - mdpi.com
Over the past two decades, percutaneous left atrial appendage occlusion (LAAO) has
proven to be a viable alternative to oral anticoagulation (OAC) for stroke prevention in …

[HTML][HTML] Comparative Effectiveness and Safety of Direct Oral Anticoagulants Compared with Warfarin in Patients with Low Bodyweight who have Atrial Fibrillation: A …

MN Elshafei, A El-Bardissy, M Salem… - American Journal of …, 2024 - Springer
Introduction oral anticoagulant (DOAC) agents are becoming the anticoagulation strategy of
choice for most clinical risks for which they are indicated. However, residual uncertainty …

Time-in-therapeutic-range defined warfarin and direct oral anticoagulants in atrial fibrillation: a Nationwide Cohort Study

M Lehto, A Luojus, O Halminen, J Haukka… - Annals of …, 2024 - Taylor & Francis
Background Little is known how individual time-in-therapeutic-range (TTR) impacts the
effectiveness and safety of warfarin therapy compared to direct oral anticoagulants (DOACs) …

Time to Benefit and Harm of Direct Oral Anticoagulants in Device-Detected Atrial Fibrillation: A Pooled Analysis of the NOAH-AFNET 6 and ARTESiA Trials

C Huang, L Li, W Liu, Y Fang, S Jiang, Y Li… - Heart Rhythm, 2024 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) reduce stroke risk in patients with
device-detected atrial fibrillation (DD-AFib) but increase major bleeding risk. The time to …

Comparative Safety and Effectiveness of Reduced Doses of Direct Acting Oral Anticoagulants for Stroke Prevention in Atrial Fibrillation

F Skjøth, TB Larsen, AR Dun, M Lilja, I Rahman… - The American Journal of …, 2024 - Elsevier
ABSTRACT Background This Nordic observational cohort study aims to assess the
effectiveness and safety of reduced-dose direct-acting oral anticoagulants (DOACs) …