The purpose of this review is to summarize essential pharmacological, pharmaceutical, and
clinical aspects in the field of orally inhaled therapies that may help scientists seeking to …

Solid dosage forms of biopharmaceuticals such as therapeutic proteins could provide
enhanced bioavailability, improved storage stability, as well as expanded alternatives to …

Therapeutic biologics such as genes, peptides, proteins, virus and cells provide clinical
benefits and are becoming increasingly important tools in respiratory medicine. Pulmonary …

For inhalation drug delivery, amorphous powder formulations offer the benefits of increased
bioavailability for poorly soluble drugs, improved biochemical stability for biologics, and …

Abstract l-Leucine (LL) has been widely used to enhance the dispersion performance of
powders for inhalation. LL can also protect powders against moisture, but this effect is much …

Spray drying is a versatile technology that has been applied widely in the chemical, food,
and, most recently, pharmaceutical industries. This review focuses on engineering advances …

Abstract A Dry Powder Inhaler (DPI) is a technique as well as a device used to inhale
formulation which is in the form of dry powder, and is inhaled through the nose or mouth. It …

Pulmonary drug delivery can have several advantages over other administration routes, in
particular when using dry powder formulations. Such dry powder inhalation formulations …

Current marketed dry powder inhalers utilize the energy from patient inspiration to fluidize
and disperse bulk powder agglomerates into respirable particles. Variations in patient …

Recent advances in formulation sciences have expanded the previously limited design
space for biological modalities, including peptide, protein, and vaccine products. At the …