Biomaterials/tissue interactions: possible solutions to overcome foreign body response

JM Morais, F Papadimitrakopoulos, DJ Burgess - The AAPS journal, 2010 - Springer
In recent years, a variety of biomaterial implantable devices has been developed. Of
particular significance to pharmaceutical sciences is the progress made on the development …

A review of the biocompatibility of implantable devices: current challenges to overcome foreign body response

Y Onuki, U Bhardwaj… - Journal of diabetes …, 2008 - journals.sagepub.com
In recent years, a variety of devices (drug-eluting stents, artificial organs, biosensors,
catheters, scaffolds for tissue engineering, heart valves, etc.) have been developed for …

Alginate-based microcapsules for immunoisolation of pancreatic islets

P de Vos, MM Faas, B Strand, R Calafiore - Biomaterials, 2006 - Elsevier
Transplantation of microencapsulated cells is proposed as a therapy for the treatment of a
wide variety of diseases since it allows for transplantation of endocrine cells in the absence …

Biocompatibility of implantable synthetic polymeric drug carriers: focus on brain biocompatibility

E Fournier, C Passirani, CN Montero-Menei, JP Benoit - Biomaterials, 2003 - Elsevier
Numerous polymeric biomaterials are implanted each year in human bodies. Among them,
drug delivery devices are potent novel powerful therapeutics for diseases which lack …

Biocompatibility of alginate–poly-l-lysine microcapsules for cell therapy

G Orive, SK Tam, JL Pedraz, JP Hallé - Biomaterials, 2006 - Elsevier
Cell microencapsulation holds promise for the treatment of many diseases by the continuous
delivery of therapeutic products. The biocompatibility of the microcapsules and their …

[图书][B] Scaffolding in tissue engineering

PX Ma, J Elisseeff - 2005 - taylorfrancis.com
The growing interest in scaffolding design and increasing research programs dedicated to
regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While …

Preparation of coated nanoparticles for a new mucosal vaccine delivery system

O Borges, G Borchard, JC Verhoef, A de Sousa… - International journal of …, 2005 - Elsevier
It has been found that the adsorption of antigens onto chitosan particles is an easy and
unique mild loading process suitable to be used with vaccines. In order to increase the …

[HTML][HTML] Polymeric approaches to reduce tissue responses against devices applied for islet-cell encapsulation

S Hu, P De Vos - Frontiers in bioengineering and biotechnology, 2019 - frontiersin.org
Immunoisolation of pancreatic islets is a technology in which islets are encapsulated in
semipermeable but immunoprotective polymeric membranes. The technology allows for …

Multiscale requirements for bioencapsulation in medicine and biotechnology

P de Vos, M Bučko, P Gemeiner, M Navrátil, J Švitel… - Biomaterials, 2009 - Elsevier
Bioencapsulation involves the envelopment of tissues or biological active substances in
semipermeable membranes. Bioencapsulation has been shown to be efficacious in …

Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination

O Borges, A Cordeiro-da-Silva, SG Romeijn… - Journal of Controlled …, 2006 - Elsevier
The design of particulate vaccine delivery systems, particularly for mucosal surfaces, has
been a focus of interest in recent years. In this context, we have previously described the …