Multimorbidity

ST Skou, FS Mair, M Fortin, B Guthrie… - Nature Reviews …, 2022 - nature.com
Multimorbidity (two or more coexisting conditions in an individual) is a growing global
challenge with substantial effects on individuals, carers and society. Multimorbidity occurs a …

Examining variation in the measurement of multimorbidity in research: a systematic review of 566 studies

ISS Ho, A Azcoaga-Lorenzo, A Akbari… - The Lancet Public …, 2021 - thelancet.com
Background A systematic understanding of how multimorbidity has been constructed and
measured is unavailable. This review aimed to examine the definition and measurement of …

Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

RA Evans, H McAuley, EM Harrison… - The Lancet …, 2021 - thelancet.com
Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …

Comparing clinical trial population representativeness to real-world populations: an external validity analysis encompassing 43 895 trials and 5 685 738 individuals …

YY Tan, V Papez, WH Chang, SH Mueller… - The Lancet Healthy …, 2022 - thelancet.com
Summary Background Randomised controlled trials (RCTs) inform prescription guidelines,
but stringent eligibility criteria exclude individuals with vulnerable characteristics, which we …

miR-21 and miR-146a: the microRNAs of inflammaging and age-related diseases

F Olivieri, F Prattichizzo, A Giuliani… - Ageing research …, 2021 - Elsevier
The first paper on “inflammaging” published in 2001 paved the way for a unifying theory on
how and why aging turns out to be the main risk factor for the development of the most …

The prevalence of psychiatric and chronic pain comorbidities in fibromyalgia: an ACTTION systematic review

BA Kleykamp, MKC Ferguson, E McNicol… - Seminars in arthritis and …, 2021 - Elsevier
Fibromyalgia (FM) is a chronic widespread pain condition that overlaps with multiple
comorbid health conditions and contributes to considerable patient distress. The aim of this …

[HTML][HTML] Measuring multimorbidity in research: Delphi consensus study

ISS Ho, A Azcoaga-Lorenzo, A Akbari, J Davies… - BMJ …, 2022 - ncbi.nlm.nih.gov
Measuring multimorbidity in research: Delphi consensus study - PMC Back to Top Skip to main
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[HTML][HTML] LSE–Lancet Commission on the future of the NHS: re-laying the foundations for an equitable and efficient health and care service after COVID-19

M Anderson, E Pitchforth, M Asaria, C Brayne… - The Lancet, 2021 - thelancet.com
The UK has recorded one of the highest death rates associated with COVID-19 globally,
whether measured as deaths that are directly attributable to COVID-19 or by excess …

Relationship between multimorbidity, demographic factors and mortality: findings from the UK Biobank cohort

BD Jani, P Hanlon, BI Nicholl, R McQueenie… - BMC medicine, 2019 - Springer
Background Multimorbidity is associated with higher mortality, but the relationship with
cancer and cardiovascular mortality is unclear. The influence of demographics and type of …

Measuring multimorbidity beyond counting diseases: systematic review of community and population studies and guide to index choice

LE Stirland, L González-Saavedra, DS Mullin… - Bmj, 2020 - bmj.com
Objectives To identify and summarise existing indices for measuring multimorbidity beyond
disease counts, to establish which indices include mental health comorbidities or outcomes …