The first clinically relevant reports of preparations of St. John's wort (SJW), a herbal medicine
with anti‐depressant effects, interacting with other drugs, altering their bioavailability and …

Ethnopharmacological relevance Hypericum species have been used traditionally as
astringent, antipyretic, diuretic, antiphlogistic, analgesic, and antidepressant in Europe …

Ethnopharmacological relevance Depression, one of the most common psychiatric
disorders, is the fourth leading cause of long-term disability worldwide. A series of causes …

Abstract Ethnopharmacological relevance Aloysia citrodora Paláu (Lippia citriodora Kunth),
commonly known as" lemon verbena" is a medicinal plant native to South America, North …

Background The usage of medicinal plants as a key component of complementary and
alternative medicine, has acquired renewed interest in developed countries. The current …

Pomegranate (Punica granatum) is an ancient perennial plant species of the Punicaceae
family and is regarded as the 'miracle fruit'for its seeds being consumed as food, juice and …

Whilst the popular use of herbal medicine globally, it poses challenges in managing
potential drug-herb interaction. There are two folds of the drug-herb interaction, a beneficial …

A new coronavirus causing severe acute respiratory syndrome (SARS-CoV-2) has emerged
and with it, a global investigation of new antiviral treatments and supportive care for organ …

Drug-metabolizing enzymes, particularly the cytochrome P450 (CYP450) monooxygenases,
play a pivotal role in pharmacokinetics. CYP450 enzymes can be affected by various …

Background Saffron has antidepressant and anxiolytic effects in adults with mild-to-
moderate depression. However, this is the first study examining its mood-related effects in …