Digital biomarkers in multiple sclerosis

A Dillenseger, ML Weidemann, K Trentzsch, H Inojosa… - Brain sciences, 2021 - mdpi.com
For incurable diseases, such as multiple sclerosis (MS), the prevention of progression and
the preservation of quality of life play a crucial role over the entire therapy period. In MS …

eHealth tools to assess the neurological function for research, in absence of the neurologist–a systematic review, part I (software)

VR Ferreira, E Metting, J Schauble, H Seddighi… - Journal of …, 2024 - Springer
Background Neurological disorders remain a worldwide concern due to their increasing
prevalence and mortality, combined with the lack of available treatment, in most cases …

Repeated forms, testing intervals, and SDMT performance in a large multiple sclerosis dataset

TA Fuchs, J Gillies, MG Jaworski III, GE Wilding… - Multiple Sclerosis and …, 2022 - Elsevier
Abstract Background The Symbol Digit Modalities Test (SDMT), the most reliable and
sensitive measure of cognition in people with multiple sclerosis (PwMS), is increasingly …

[HTML][HTML] Assessing cognitive function in multiple sclerosis with digital tools: observational study

WY Hsu, W Rowles, JA Anguera, A Anderson… - Journal of Medical …, 2021 - jmir.org
Background Cognitive impairment (CI) is one of the most prevalent symptoms of multiple
sclerosis (MS). However, it is difficult to include cognitive assessment as part of MS standard …

Disease-modifying therapy initiation patterns in multiple sclerosis in three large MS populations

A Stahmann, E Craig, D Ellenberger… - Therapeutic …, 2024 - journals.sagepub.com
Background: Treatment guidelines recommend early disease-modifying therapy (DMT)
initiation after diagnosis of multiple sclerosis (MS). Multinational comparative studies that …

Digital phenotyping in clinical neurology

AS Gupta - Seminars in neurology, 2022 - thieme-connect.com
Internet-connected devices, including personal computers, smartphones, smartwatches, and
voice assistants, have evolved into powerful multisensor technologies that billions of people …

Patient-reported outcomes in multiple sclerosis: a prospective registry cohort study

A Lerede, J Rodgers, RM Middleton… - Brain …, 2023 - academic.oup.com
Registries have the potential to tackle some of the current limitations in determining the long-
term impact of multiple sclerosis. Online assessments using patient-reported outcomes can …

Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): protocol for a mixed-methods, multicentre feasibility randomised controlled trial

G Topcu, L Smith, JR Mhizha-Murira, N Goulden… - Pilot and Feasibility …, 2022 - Springer
Background Cognitive problems affect up to 70% of people with multiple sclerosis (MS),
which can negatively impact mood, ability to work, and quality of life. Addressing cognitive …

Clinical Applicability of Cognitive Testing in Huntington Disease

A Mühlbäck - 2023 - dspace.cuni.cz
Introduction: Huntington disease (HD) is an autosomal dominant neurodegenerative
disorder manifested by motor, behavioural and cognitive deficits with fatal consequences …

[PDF][PDF] Digital Biomarkers in Multiple Sclerosis. Brain Sci. 2021, 11, 1519

A Dillenseger, ML Weidemann, K Trentzsch… - Digital innovation in …, 2021 - mdpi.com
For incurable diseases, such as multiple sclerosis (MS), the prevention of progression and
the preservation of quality of life play a crucial role over the entire therapy period. In MS …