Together with fibroblast growth factors (FGFs) 19 and 21, FGF23 is an endocrine member of
the family of FGFs. Mainly secreted by bone cells, FGF23 acts as a hormone on the kidney …

Hyperphosphatemia is a serious complication in patients with chronic kidney disease (CKD),
and is associated with more rapid progression as well as higher risk of mortality, and higher …

Inorganic phosphate (Pi) is an essential nutrient for human health. Due to the changes in our
dietary pattern, dietary Pi overload engenders systemic phosphotoxicity, including excessive …

Phosphate is a common ingredient of the daily consumed foods and is absorbed in the
intestine and is excreted in the urine through the kidney to maintain the homeostatic …

Phosphate, an essential nutrient, is available in organic and inorganic forms. The balance of
phosphate is central for cellular homeostasis through the genomic roles of DNA and RNA …

Hyperphosphatemia has been proposed as a cardiovascular risk factor, contributing to long-
term vascular calcification in hyperphosphatemic Chronic Kidney Disease (CKD) patients …

One of the main regulators of phosphate homeostasis is fibroblast growth factor 23 (FGF23),
secreted by osteocytes. The effects of organic versus inorganic dietary phosphate on this …

This chapter provides a review of the main types of bioactive ceramics and glasses used or
under development for tissue engineering applications. Bioactive ceramics and glasses …

Hyperphosphataemia increases cardiovascular mortality in patients with kidney disease.
Direct effects of high inorganic phosphate (Pi) concentrations have previously been …

The past decades have seen rapid developments in nanomedicine, but the therapeutic
efficacy of nanosized anti-cancer agents remains marginal, although some have reached …