Organic neuroelectronics: from neural interfaces to neuroprosthetics

GT Go, Y Lee, DG Seo, TW Lee - Advanced Materials, 2022 - Wiley Online Library
Requirements and recent advances in research on organic neuroelectronics are outlined
herein. Neuroelectronics such as neural interfaces and neuroprosthetics provide a …

Bioelectronic medicine: Preclinical insights and clinical advances

VA Pavlov, KJ Tracey - Neuron, 2022 - cell.com
The nervous system maintains homeostasis and health. Homeostatic disruptions underlying
the pathobiology of many diseases can be controlled by bioelectronic devices targeting CNS …

Durability of clinical and quality-of-life outcomes of closed-loop spinal cord stimulation for chronic back and leg pain: a secondary analysis of the evoke randomized …

N Mekhail, RM Levy, TR Deer, L Kapural, S Li… - JAMA …, 2022 - jamanetwork.com
Importance Chronic pain is debilitating and profoundly affects health-related quality of life.
Spinal cord stimulation (SCS) is a well-established therapy for chronic pain; however, SCS …

Implanted spinal neuromodulation interventions for chronic pain in adults

NE O'Connell, MC Ferraro, W Gibson… - Cochrane Database …, 2021 - cochranelibrary.com
Background Implanted spinal neuromodulation (SNMD) techniques are used in the
treatment of refractory chronic pain. They involve the implantation of electrodes around the …

Modulation of neuroglial interactions using differential target multiplexed spinal cord stimulation in an animal model of neuropathic pain

R Vallejo, CA Kelley, A Gupta, WJ Smith… - Molecular …, 2020 - journals.sagepub.com
The development and maintenance of chronic neuropathic pain involves distorted neuroglial
interactions, which result in prolonged perturbations of immune and inflammatory response …

Novel therapies for the treatment of neuropathic pain: potential and pitfalls

P Shinu, MA Morsy, AB Nair, AKA Mouslem… - Journal of Clinical …, 2022 - mdpi.com
Neuropathic pain affects more than one million people across the globe. The quality of life of
people suffering from neuropathic pain has been considerably declining due to the …

[HTML][HTML] Research design considerations for randomized controlled trials of spinal cord stimulation for pain: Initiative on Methods, Measurement, and Pain Assessment …

N Katz, RH Dworkin, R North, S Thomson, S Eldabe… - Pain, 2021 - journals.lww.com
Spinal cord stimulation (SCS) is an interventional nonpharmacologic treatment used for
chronic pain and other indications. Methods for evaluating the safety and efficacy of SCS …

Neuromodulation therapy for chemotherapy-induced peripheral neuropathy: a systematic review

RS D'Souza, YF Her, MY Jin, M Morsi, A Abd-Elsayed - Biomedicines, 2022 - mdpi.com
Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating and painful condition
in patients who have received chemotherapy. The role of neuromodulation therapy in …

Anatomical and technical factors affecting the neural response to epidural spinal cord stimulation

HJ Zander, RD Graham, CJ Anaya… - Journal of neural …, 2020 - iopscience.iop.org
Objective. Spinal cord stimulation (SCS) is a common neurostimulation therapy to treat
chronic pain. Computational models represent a valuable tool to study the potential …

Using a high-frequency carrier does not improve comfort of transcutaneous spinal cord stimulation

AN Dalrymple, CA Hooper, MG Kuriakose… - Journal of Neural …, 2023 - iopscience.iop.org
Objective. Spinal cord neuromodulation has gained much attention for demonstrating
improved motor recovery in people with spinal cord injury, motivating the development of …