[HTML][HTML] Multi-session transcutaneous spinal cord stimulation prevents chloride homeostasis imbalance and the development of hyperreflexia after spinal cord injury in …

DC Malloy, MP Côté - Experimental neurology, 2024 - Elsevier
Spasticity is a complex and multidimensional disorder that impacts nearly 75% of individuals
with spinal cord injury (SCI) and currently lacks adequate treatment options. This …

The pathways and processes underlying spinal transmission of low back pain: observations from dorsal root ganglion stimulation treatment

KB Chapman, PS Groenen, KC Vissers… - … : Technology at the …, 2021 - Elsevier
Background Dorsal root ganglion stimulation (DRG-S) is a novel approach to treat chronic
pain. Lead placement at L2 has been reported to be an effective treatment for axial low back …

[HTML][HTML] Neural recruitment during conventional, burst, and 10-kHz spinal cord stimulation for pain

ER Rogers, HJ Zander, SF Lempka - The journal of pain, 2022 - Elsevier
Spinal cord stimulation (SCS) is a popular neurostimulation therapy for severe chronic pain.
To improve stimulation efficacy, multiple modes are now used clinically, including …

Transcranial direct current stimulation alleviates nociceptive behavior in male rats with neuropathic pain by regulating oxidative stress and reducing …

G Akcay, D Nemutlu Samur… - Journal of Neuroscience …, 2023 - Wiley Online Library
Transcranial direct curent stimulation (tDCS) and trans‐spinal direct current stimulation
(tsDCS) are promising therapies for pain that can alter the excitability of neuronal activity in …

Miniature battery-free epidural cortical stimulators

JE Woods, AL Singer, F Alrashdan, W Tan, C Tan… - Science …, 2024 - science.org
Miniaturized neuromodulation systems could improve the safety and reduce the
invasiveness of bioelectronic neuromodulation. However, as implantable bioelectronic …

The role of neuro-immune interactions in chronic pain: implications for clinical practice

PYP Su, L Zhang, L He, N Zhao… - Journal of Pain Research, 2022 - Taylor & Francis
Chronic pain remains a public health problem and contributes to the ongoing opioid
epidemic. Current pain management therapies still leave many patients with poorly …

Degeneracy in the nervous system: from neuronal excitability to neural coding

MA Kamaleddin - BioEssays, 2022 - Wiley Online Library
Degeneracy is ubiquitous across biological systems where structurally different elements
can yield a similar outcome. Degeneracy is of particular interest in neuroscience too. On the …

Very low frequencies maintain pain relief from dorsal root ganglion stimulation: an evaluation of dorsal root ganglion neurostimulation frequency tapering

KB Chapman, TA Yousef, KC Vissers… - … : Technology at the …, 2021 - Elsevier
Background Dorsal root ganglion neurostimulation (DRG-S) is effective in treating various
refractory chronic pain syndromes. In preclinical studies, DRG-S at very low frequencies (< 5 …

Explantation rates of high frequency spinal cord stimulation in two outpatient clinics

VC Wang, V Bounkousohn, K Fields… - … : Technology at the …, 2021 - Elsevier
Objectives To report the explantation rates of high frequency 10 kHz spinal cord stimulation
(SCS) in a real-world setting. Materials and Methods This is a retrospective review of …

[HTML][HTML] Disease applications of spinal cord stimulation: Chronic nonmalignant pain

F Sammartino, J MacDonell, RB North, V Krishna… - …, 2024 - Elsevier
Neuropathic pain is a chronic condition representing a significant burden for society. It is
estimated 1 out of 10 people over the age of 30 that in the US have been diagnosed with …