While paresthesia-based Spinal Cord Stimulation (SCS) has been proven effective as
treatment for chronic neuropathic pain, its initial benefits may lead to the development of …

Background Neuropathic pain is caused by primary lesion or dysfunction of either peripheral
or central nervous system. Due to its complex pathogenesis, often related to a number of …

Persistent pain after spinal surgery can be successfully addressed by spinal cord stimulation
(SCS). International guidelines strongly recommend that a lead trial be performed before …

Background Dorsal root ganglion stimulation (DRG‐S) is used as a treatment for chronic low‐
back pain (CLBP), although its underlying mechanisms remain elusive. CLBP patients have …

Background Spinal cord stimulation (SCS) has been suggested as a treatment option to
improve the quality-adjusted life years of individuals with low back pain. However, previous …

Background Restless legs syndrome (RLS) is a prevalent sensorimotor disorder that can
dramatically impair sleep quality, daytime function, and quality of life. Although many …

Parkinson's disease (PD) is a progressive neurodegenerative disease with an incidence of
0.1 to 0.2% over the age of 40 and a prevalence of over 1 million people in North America …

The roles of Aβ low-threshold mechanoreceptors (LTMRs) in transmitting mechanical
hyperalgesia and in alleviating chronic pain have been of great interest but remain …

A narrative review and future considerations of spinal cord... : Current Opinion in
Anesthesiology A narrative review and future considerations of spinal cord stimulation …

Glial cells play an essential role in maintaining the proper functioning of the nervous system.
They are more abundant than neurons in most neural tissues and provide metabolic and …