Non-spinal neuromodulation of the lumbar medial branch nerve for chronic axial low back pain: a narrative review

V Tieppo Francio, BD Westerhaus, A Rupp… - Frontiers in Pain …, 2022 - frontiersin.org
Chronic low back pain remains highly prevalent, costly, and the leading cause of disability
worldwide. Symptoms are complex and treatment involves an interdisciplinary approach …

[HTML][HTML] Spinal cord stimulator implant

AM Dydyk, P Tadi - 2020 - europepmc.org
Objectives: Identify the indications and contraindications for spinal cord stimulator
implantation. Describe the technique of spinal cord stimulator implantation. Review the …

[HTML][HTML] Heterogeneous cortical effects of spinal cord stimulation

B Witjes, S Baillet, M Roy, R Oostenveld… - … : Technology at the …, 2023 - Elsevier
Objectives The understanding of the cortical effects of spinal cord stimulation (SCS) remains
limited. Multiple studies have investigated the effects of SCS in resting-state …

What is the role of frequency on neural activation in tonic stimulation in SCS therapy? A computational study on sensory Aβ nerve fibers

C Solanes, JL Durá, J De Andrés, J Saiz - IEEE Access, 2021 - ieeexplore.ieee.org
The investigation of the effect of the stimulation parameters by computational modeling
helps to understand the electrical response of specific neural elements in Spinal Cord …

Stimulation of the dorsal root ganglion using an Injectrode®

AN Dalrymple, JE Ting, R Bose… - Journal of neural …, 2021 - iopscience.iop.org
Objective. The goal of this work was to compare afferent fiber recruitment by dorsal root
ganglion (DRG) stimulation using an injectable polymer electrode (Injectrode®) and a more …

Signal transmission analysis in implantable human body communication for abdominal medical devices

D Muramatsu, M Kodama - AIP Advances, 2023 - pubs.aip.org
Implantable medical devices, such as neurostimulators, need to be wirelessly controlled
from outside the body. Many of these devices use high-frequency signals in the 400 MHz …

Spinal Cathepsin S promotes visceral hypersensitivity via FKN/CX3CR1/p38 MAPK signaling pathways

P Sun, W Lin, Y Weng, J Gong, Y Huang… - Molecular …, 2023 - journals.sagepub.com
Background Irritable bowel syndrome (IBS) is one of the typical representatives of chronic
functional visceral pain that lacks effective treatment. Recently, attention has been given to …

Electrochemical impedance spectroscopy as a tool for monitoring cell differentiation from floor plate progenitors to midbrain neurons in real time

A Elghajiji, X Wang, SD Weston, G Zeck… - Advanced …, 2021 - Wiley Online Library
Here shows that electrical impedance spectroscopy can be used as a non‐invasive and real
time tool to probe cell adhesion and differentiation from midbrain floor plate progenitors into …

Five reasons why some herniated intervertebral discs are painless

DA Shin, MC Chang - Journal of Pain Research, 2023 - Taylor & Francis
Herniated intervertebral discs (HIVDs) can cause lower back pain and leg pain, but not all
cases are painful. We suggest five potential reasons for painless HIVDs. First, when …

Real World Clinical Utility of Neurophysiological Measurement Utilizing Closed-Loop Spinal Cord Stimulation in a Chronic Pain Population: The ECAP Study Protocol

A Leitner, E Hanson, N Soliday, P Staats… - Journal of Pain …, 2023 - Taylor & Francis
Background Spinal cord stimulation (SCS) is an established chronic pain treatment, but the
effectiveness of traditional, open-loop paradigms has been plagued by variable …