Background The human gut hosts complex microbial communities, which are linked to
health and disease. The gut microbiota is continuously reshaped by multiple environmental …

Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

Depression is the most prevalent mental disorder in the world associated with huge socio-
economic consequences. While depressive-related symptoms are well known, the …

Inflammatory bowel disease represents one of the most life-altering gastrointestinal
pathologies, with its multifactorial nature and unclear physiopathology. The most relevant …

The use of probiotics, prebiotics, synbiotics or fermented foods can modulate the gut-brain
axis and constitute a potentially therapeutic intervention in psychiatric disorders. This …

In this study, a systematic review of randomized clinical trials conducted from January 2000
to December 2023 was performed to examine the efficacy of psychobiotics—probiotics …

Mounting evidence points towards a crucial role of the kynurenine pathway (KP) in the
altered gut-brain axis (GBA) balance in severe mental illness (SMI, namely depression …

Objective Accumulating evidence indicates that oxidative stress and the disruption of
antioxidant defenses play an important role in the neurobiology of bipolar disorder (BD) …

Introduction A novel new area of exploration in the treatment of bipolar disorder is the gut
brain axis. Studies have shown significant differences between the gut microbiome in those …

Background There is growing evidence suggesting a connection between gut dysbiosis and
the development of psychiatric disorders. A number of studies have shown that probiotics …