[图书][B] Adenosine receptors and the heart: role in regulation of coronary blood flow and cardiac electrophysiology

SJ Mustafa, RR Morrison, B Teng, A Pelleg - 2009 - Springer
Adenosine is an autacoid that plays a critical role in regulating cardiac function, including
heart rate, contractility, and coronary flow. In this chapter, current knowledge of the functions …

Proarrhythmic effects of adenosine: one decade of clinical data

A Pelleg, RS Pennock, SP Kutalek - American journal of …, 2002 - journals.lww.com
In 1989, adenosine was introduced into the American clinical setting as an antiarrhythmic
drug for the acute management of reentrant supraventricular tachycardia involving the …

[HTML][HTML] Pretreatment with an adenosine A1 receptor agonist and lidocaine: a possible alternative to myocardial ischemic preconditioning

SJ Canyon, GP Dobson - The Journal of thoracic and cardiovascular …, 2005 - Elsevier
OBJECTIVE: The heart possesses an extraordinary ability to remember short episodes of
sublethal ischemia and reperfusion (angina), which protects the myocardium and coronary …

Organ preconditioning, arrest, protection, preservation and recovery

G Dobson - US Patent App. 10/539,222, 2006 - Google Patents
US20060034941A1 - Organ preconditioning, arrest, protection, preservation and recovery -
Google Patents US20060034941A1 - Organ preconditioning, arrest, protection, preservation …

Adenosine receptors and cardiovascular disease: The adenosine-1 receptor (A1) and A1 selective ligands

ES Hayes - Cardiovascular Toxicology, 2003 - Springer
Adenosine has often been cited as a universal “retaliatory metabolite” against the
destructive cellular mechanisms that are initiated during metabolic/oxidative stress. Despite …

Organ preconditioning, arrest, protection, preservation and recovery (2)

GP Dobson - US Patent App. 13/935,882, 2014 - Google Patents
The present invention relates to a method for reducing elec trical disturbance of a cells
resting membrane potential com prising administering an effective amount of a composition …

Organ preconditioning, arrest, protection, preservation and recovery

GP Dobson - US Patent App. 12/472,069, 2009 - Google Patents
Jun. 17, 2005, now abandoned, filed as application No. comprising an effective amount of a
local anaesthetic and of PCT/AU2003/001711 on Dec. 22, 2003. one or more of a potassium …

Regulation of adenosine receptor subtypes and cardiac dysfunction in human heart failure

B Stein, J Kiehn, J Neumann - Cardiovascular biology of purines, 1998 - Springer
A defective adenosine receptor-mediated autoregulation of the heart has been hypothesized
to cause cardiomyopathy. Regulation of gene expression of the four adenosine receptor …

Effects of adenosine A1 receptor agonist CCPA and antagonist DPCPX on ischemia/reperfusion-induced arrhythmias in rats

Ö Bozdoğan, E Gonca… - Turkish Journal of Medical …, 2010 - journals.tubitak.gov.tr
Adenosine has been commonly used to treat supraventricular tachycardia in clinics.
However, there are only a few studies on the effects of adenosine on ischemia or …

Organ preconditioning, arrest, protection, preservation and recovery

GP Dobson - US Patent App. 15/203,456, 2016 - Google Patents
The present invention relates to a method for reducing electrical disturbance of a cell's
resting membrane potential comprising administering an effective amount of a composition …