Second-generation antipsychotics (SGAs) are the cornerstone of treatment for schizophrenia
because of their high clinical efficacy. However, SGA treatment is associated with severe …

Mitochondria play a critical role in regulating cellular functions including bioenergetics,
calcium homeostasis, redox signalling, and apoptotic cell death. Mitochondria are also …

Almost fifty years after its first introduction into clinical care, clozapine remains the only
evidence-based pharmacological option for treatment-resistant schizophrenia (TRS), which …

Fasting hyperglycemia, impaired glucose tolerance, prediabetes, and diabetes are
frequently present in patients treated with second-generation antipsychotics (SGAPs) for …

The second generation antipsychotic drug clozapine represents the most effective
pharmacotherapy for treatment-resistant psychosis. It is also associated with low rates of …

Obesity represents an important public health concern because it substantially increases the
risk of multiple chronic diseases and thereby contributing to a decline in both quality of life …

Optical coherence tomography (OCT) has been recently used to investigate
neuropsychiatric disorders. We aimed to study retinal OCT measures of patients with …

The use of antipsychotic drugs for the treatment of mood disorders and psychosis has
increased dramatically over the last decade. Despite its consumption being associated with …

Antipsychotic drugs (APDs) are widely prescribed to control various mental disorders. As
mental disorders are chronic diseases, these drugs are often used over a life-time. However …

Objectives: The objective of this systematic review was to synthetize the published data on
the relationships between elevated blood C-reactive protein (CRP) levels and schizophrenia …