Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations

YY Teo, X Sim, RTH Ong, AKS Tan, J Chen… - Genome …, 2009 - genome.cshlp.org
The Singapore Genome Variation Project (SGVP) provides a publicly available resource of
1.6 million single nucleotide polymorphisms (SNPs) genotyped in 268 individuals from the …

Characterizing the admixed African ancestry of African Americans

F Zakharia, A Basu, D Absher, TL Assimes, AS Go… - Genome biology, 2009 - Springer
Background Accurate, high-throughput genotyping allows the fine characterization of
genetic ancestry. Here we applied recently developed statistical and computational …

An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility

L Wang, TJ Balmat, AL Antonia, FJ Constantine… - Genome medicine, 2021 - Springer
Background While genome-wide associations studies (GWAS) have successfully elucidated
the genetic architecture of complex human traits and diseases, understanding mechanisms …

Evolution, revolution and heresy in the genetics of infectious disease susceptibility

AVS Hill - … Transactions of the Royal Society B: Biological …, 2012 - royalsocietypublishing.org
Infectious pathogens have long been recognized as potentially powerful agents impacting
on the evolution of human genetic diversity. Analysis of large-scale case–control studies …

Blood groups and malaria: fresh insights into pathogenesis and identification of targets for intervention

JA Rowe, DH Opi, TN Williams - Current opinion in hematology, 2009 - journals.lww.com
Blood groups and malaria: fresh insights into pathogenesis a... : Current Opinion in Hematology
Blood groups and malaria: fresh insights into pathogenesis and identification of targets for …

H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa

NJ Mulder, E Adebiyi, R Alami, A Benkahla… - Genome …, 2016 - genome.cshlp.org
The application of genomics technologies to medicine and biomedical research is
increasing in popularity, made possible by new high-throughput genotyping and sequencing …

Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis

S Mahasirimongkol, H Yanai, T Mushiroda… - Journal of human …, 2012 - nature.com
Tuberculosis (TB) is one of the most devastating chronic infectious diseases, but the role of
host genetics in disease development after infection in this disease remains unidentified …

Leveraging Mann–Whitney U test on large-scale genetic variation data for analysing malaria genetic markers

KY Tai, J Dhaliwal, V Balasubramaniam - Malaria Journal, 2022 - Springer
Background The malaria risk analysis of multiple populations is crucial and of great
importance whilst compressing limitations. However, the exponential growth in diversity and …

[HTML][HTML] High levels of Plasmodium falciparum rosetting in all clinical forms of severe malaria in African children

OK Doumbo, MA Thera, AK Koné, A Raza… - The American journal …, 2009 - ncbi.nlm.nih.gov
Plasmodium falciparum rosetting (the spontaneous binding of infected erythrocytes to
uninfected erythrocytes) is a well-recognized parasite virulence factor. However, it is …

Heme cytotoxicity and the pathogenesis of immune-mediated inflammatory diseases

R Larsen, Z Gouveia, MP Soares… - Frontiers in …, 2012 - frontiersin.org
Heme, iron (Fe) protoporphyrin IX, functions as a prosthetic group in a range of
hemoproteins essential to support life under aerobic conditions. The Fe contained within the …