[HTML][HTML] Tumor angiogenesis and anti-angiogenic strategies for cancer treatment
Angiogenesis is the process through which novel blood vessels are formed from pre-existing
ones and it is involved in both physiological and pathological processes of the body …
ones and it is involved in both physiological and pathological processes of the body …
[HTML][HTML] Exosomes in angiogenesis and anti-angiogenic therapy in cancers
W Olejarz, G Kubiak-Tomaszewska… - International Journal of …, 2020 - mdpi.com
Angiogenesis is the process through which new blood vessels are formed from pre-existing
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …
[HTML][HTML] Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment
G Werba, D Weissinger, EA Kawaler, E Zhao… - Nature …, 2023 - nature.com
The tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC) is a
complex ecosystem that drives tumor progression; however, in-depth single cell …
complex ecosystem that drives tumor progression; however, in-depth single cell …
Surufatinib in advanced pancreatic neuroendocrine tumours (SANET-p): a randomised, double-blind, placebo-controlled, phase 3 study
J Xu, L Shen, C Bai, W Wang, J Li, X Yu, Z Li… - The Lancet …, 2020 - thelancet.com
Background Surufatinib showed superior efficacy in extrapancreatic neuroendocrine
tumours (NETs) in the phase 3 SANET-ep study. In SANET-p, we aimed to assess the …
tumours (NETs) in the phase 3 SANET-ep study. In SANET-p, we aimed to assess the …
[HTML][HTML] Novel drugs with high efficacy against tumor angiogenesis
S Qi, S Deng, Z Lian, K Yu - International Journal of Molecular Sciences, 2022 - mdpi.com
Angiogenesis is involved in physiological and pathological processes in the body. Tumor
angiogenesis is a key factor associated with tumor growth, progression, and metastasis …
angiogenesis is a key factor associated with tumor growth, progression, and metastasis …
[HTML][HTML] Dual roles and therapeutic potential of Keap1-Nrf2 pathway in pancreatic cancer: a systematic review
Pancreatic cancer (PC) is one of the most fatal diseases with a very high rate of metastasis
and low rate of survival. Despite the advances in understanding this devastating disease …
and low rate of survival. Despite the advances in understanding this devastating disease …
[HTML][HTML] Glutamine synthetase as a therapeutic target for cancer treatment
GW Kim, DH Lee, YH Jeon, J Yoo, SY Kim… - International journal of …, 2021 - mdpi.com
The significance of glutamine in cancer metabolism has been extensively studied. Cancer
cells consume an excessive amount of glutamine to facilitate rapid proliferation. Thus …
cells consume an excessive amount of glutamine to facilitate rapid proliferation. Thus …
[HTML][HTML] Autophagy: a key player in pancreatic cancer progression and a potential drug target
J Gillson, YS Abd El-Aziz, LYW Leck, PJ Jansson… - Cancers, 2022 - mdpi.com
Simple Summary With the mortality rate of pancreatic cancer predicted to rise over the
coming years, it is essential that effective treatment strategies are developed as soon as …
coming years, it is essential that effective treatment strategies are developed as soon as …
[HTML][HTML] The state-of-the-art of phase II/III clinical trials for targeted pancreatic cancer therapies
A Garcia-Sampedro, G Gaggia, A Ney… - Journal of Clinical …, 2021 - mdpi.com
Pancreatic cancer is a devastating disease with very poor prognosis. Currently, surgery
followed by adjuvant chemotherapy represents the only curative option which, unfortunately …
followed by adjuvant chemotherapy represents the only curative option which, unfortunately …
[HTML][HTML] Role of Nrf2 in pancreatic cancer
M Cykowiak, V Krajka-Kuźniak - Antioxidants, 2021 - mdpi.com
Pancreatic tumors are a serious health problem with a 7% mortality rate worldwide.
Inflammatory processes and oxidative stress play important roles in the development of …
Inflammatory processes and oxidative stress play important roles in the development of …