As the number of patients with Alzheimer's disease (AD) increases, it brings great suffering
to their families and causes a heavy socioeconomic burden to society. A vast amount of …

Aging is the greatest risk factor for late-onset Alzheimer's disease (LOAD), which accounts
for> 95% of Alzheimer's disease (AD) cases. The mechanism underlying the aging-related …

Alzheimer disease (AD) is a major cause of age-related dementia. We do not fully
understand AD aetiology and pathogenesis, but oxidative damage is a key component. The …

Oxidative stress is known to play an important role in the pathogenesis of a number of
diseases. In particular, it is linked to the etiology of Alzheimer's disease (AD), an age-related …

A major feature of Alzheimer's disease (AD) pathology is the plaque composed of
aggregated amyloid-β (Aβ) peptide. Although these plaques may have harmful properties …

Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

Alzheimer's disease (AD) is a neurodegenerative disorder accounting for over 50% of all
dementia patients and representing a leading cause of death worldwide for the global …

Alzheimer's disease (AD) is the most common form of dementia in the elderly followed by
vascular dementia. In addition to clinically diagnosed dementia, cognitive dysfunction has …

Alzheimer's disease (AD) is an incurable neurodegenerative disease. Numerous studies
have demonstrated a critical role for dysregulated glucose metabolism in its pathogenesis …

Highlights•Oxidative stress is an etiopathogenic event upstream to Aβ-plaques and
neurofibrillary tangles leading to Alzheimer's disease.•Unquenched ROS perturb the …