Mass spectrometry imaging of biomolecular information

B Spengler - Analytical chemistry, 2015 - ACS Publications
Mass spectrometry imaging (MSI) has gone through a significant change over the last 3
years, the time span of this review. The predominant mass spectrometric method in …

Lipid imaging by mass spectrometry–a review

D Gode, DA Volmer - Analyst, 2013 - pubs.rsc.org
Mass spectrometry imaging (MSI) has proven to be extremely useful for applications such as
the spatial analysis of peptides and proteins in biological tissue, the performance …

[HTML][HTML] Multimodal high-resolution nano-DESI MSI and immunofluorescence imaging reveal molecular signatures of skeletal muscle fiber types

D Unsihuay, H Hu, J Qiu, A Latorre-Palomino… - Chemical …, 2023 - pubs.rsc.org
The skeletal muscle is a highly heterogeneous tissue comprised of different fiber types with
varying contractile and metabolic properties. The complexity in the analysis of skeletal …

Applications of mass spectrometry for cellular lipid analysis

C Wang, M Wang, X Han - Molecular BioSystems, 2015 - pubs.rsc.org
Mass spectrometric analysis of cellular lipids is an enabling technology for lipidomics, which
is a rapidly-developing research field. In this review, we briefly discuss the principles …

Intramyocellular lipid droplets and insulin sensitivity, the human perspective

A Gemmink, BH Goodpaster, P Schrauwen… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Skeletal muscle can store excess fat as subcellular lipid droplets (LDs). While originally
viewed as uninteresting static balls of triacylglycerol, it is now clear that myocellular LDs play …

Changes in Tissue Distribution of Tetrodotoxin and Its Analogues in Association with Maturation in the Toxic Flatworm, Planocera multitentaculata

H Oyama, M Ito, R Suo, N Goto-Inoue, M Morisasa… - Marine …, 2022 - Springer
The toxic flatworm, Planocera multitentaculata, possesses highly concentrated tetrodotoxin
(TTX), also known as pufferfish toxin, throughout its life cycle, including the egg and larval …

[HTML][HTML] Lipidomics analysis revealed the phospholipid compositional changes in muscle by chronic exercise and high-fat diet

N Goto-Inoue, K Yamada, A Inagaki, Y Furuichi… - Scientific reports, 2013 - nature.com
Although it is clear that lipids are responsible for insulin resistance, it is poorly understood
what types of lipids are involved. In this study, we verified the characteristic lipid species in …

Long‐chain acyl‐CoA synthetase 6 regulates lipid synthesis and mitochondrial oxidative capacity in human and rat skeletal muscle

BG Teodoro, IH Sampaio, LHM Bomfim… - The Journal of …, 2017 - Wiley Online Library
Key points Long‐chain acyl‐CoA synthetase 6 (ACSL6) mRNA is present in human and rat
skeletal muscle, and is modulated by nutritional status: exercise and fasting decrease …

MALDI imaging mass spectrometry—a mini review of methods and recent developments

C Eriksson, N Masaki, I Yao, T Hayasaka… - Mass Spectrometry, 2013 - jstage.jst.go.jp
As the only imaging method available, Imaging Mass Spectrometry (IMS) can determine
both the identity and the distribution of hundreds of molecules on tissue sections, all in one …

Effect of antioxidant supplementation on skeletal muscle and metabolic profile in aging mice

S Tsukamoto-Sen, S Kawakami, H Maruki-Uchida… - Food & Function, 2021 - pubs.rsc.org
Aging induces drastic changes in muscle mass and function (sarcopenia); however, the
detailed mechanisms underlying sarcopenia remain poorly understood. Recent studies …