Using molecular similarity to highlight the challenges of routine immunoassay-based drug of abuse/toxicology screening in emergency medicine

MD Krasowski, AF Pizon, MG Siam… - BMC emergency …, 2009 - Springer
Background Laboratory tests for routine drug of abuse and toxicology (DOA/Tox) screening,
often used in emergency medicine, generally utilize antibody-based tests (immunoassays) …

A validated spectrofluorimetric method for determination of some psychoactive drugs

FA Mohamed, HA Mohamed, SA Hussein… - … of pharmaceutical and …, 2005 - Elsevier
Five psychoactive drugs namely, chlorpromazine HCl, thioridazine HCl, clomipramine HCl,
imipramine HCl and desipramine HCl were analyzed by a simple spectrofluorimetric …

Drug level monitoring: antidepressants

RN Gupta - Journal of Chromatography B: Biomedical Sciences …, 1992 - Elsevier
The determination of antidepressant drugs which act by blocking neuronal uptake of
biogenic amines, because of their widespread use and high toxicity, remains one of the most …

[图书][B] Postmortem toxicology of abused drugs

F MD, SB Karch - 2007 - api.taylorfrancis.com
Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you
need at an affordable price. Postmortem Toxicology of Abused Drugs considers the role of …

Ultrasensitive label-free immunoassay for optical determination of amitriptyline and related tricyclic antidepressants in human serum

AK Krieg, G Gauglitz - Analytical chemistry, 2015 - ACS Publications
The present work focuses on the development of a label-free and ultrasensitive
immunoassay for the detection of the drug amitriptyline in human serum. Reflectometric …

Cardiac toxicity from intentional ingestion of pong-pong seeds (Cerbera odollam)

ME Wermuth, R Vohra, N Bowman, RB Furbee… - The Journal of …, 2018 - Elsevier
Background A variety of plants contain cardiac glycosides. This has resulted in many of them
being used to commit suicide. In southeast Asia, Cerebera odollam (pong-pong or suicide …

Dual ultraviolet wavelength high-performance liquid chromatographic method for the forensic or clinical analysis of seventeen antidepressants and some selected …

IM McIntyre, CV King, S Skafidis… - Journal of Chromatography …, 1993 - Elsevier
A sensitive method suitable for the determination of tricyclic and other antidepressants in
postmortem and clinical specimens is presented. The procedure, which utilizes reversed …

Application of a novel form of solid-phase sorbent (Empore® membrane) to the isolation of tricyclic antidepressant drugs from blood

GL Lensmeyer, DA Wiebe… - Journal of …, 1991 - academic.oup.com
We employed a new form of solid-phase material, the Empore® octyl (C8) extraction
membrane (SPEM), for the efficient extraction of tricyclic drugs from patients' serum …

Non-aqueous capillary electrophoresis of biological samples after at-line solid-phase extraction

JR Veraart, MC Reinders, H Lingeman, UAT Brinkman - Chromatographia, 2000 - Springer
Solid-phase extraction (SPE) was coupled at-line to capillary electrophoresis (CE) for the
determination of a series of basic test compounds (ie tricyclic antidepressants). The analysis …

Laboratory diagnosis of poisonings

R Wennig - Human Toxicology. Descotes J. Elsevier Ed, 1996 - books.google.com
The role the toxicology laboratory has to play in the diagnosis, management and follow-up of
acute poisonings, is currently a highly controversial issue. A long, but not exhaustive, list of …