Executive summary Far-reaching changes to the structure and function of the Earth's natural
systems represent a growing threat to human health. And yet, global health has mainly …

Summary Background By August, 2021, South Africa had been affected by three waves of
SARS-CoV-2; the second associated with the beta variant and the third with the delta …

Background: Monitoring progress toward global treatment targets using HIV programme
data in sub-Saharan Africa has proved challenging. Constraints in routine data collection …

Background Cash transfers have been proposed as an intervention to reduce HIV-infection
risk for young women in sub-Saharan Africa. However, scarce evidence is available about …

Mobile phones have the potential to improve access to healthcare information and services
in low-resourced settings. This study investigated the use of mobile phones among patients …

Background The burden of kidney disease in many African countries is unknown. Equations
used to estimate kidney function from serum creatinine have limited regional validation. We …

Background Data on influenza community burden and transmission are important to plan
interventions especially in resource-limited settings. However, data are limited, particularly …

Study design HAALSI is a population-based community observational study with
longitudinal follow-up at 3-year intervals. Embedded in the study are several randomized …

Executive function is foundational for cognitive development. Previous research has shown
both gross motor skills and physical activity to be related to executive function. However …

A greater knowledge of the burden of HIV in rural areas of Southern Africa is needed,
especially among older adults. We conducted a cross-sectional biomarker survey in the rural …