The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical
research based on biologically accurate screening approaches. Since establishing the 2D in …

The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Non-alcoholic fatty liver disease (NAFLD) represents a global healthcare challenge,
affecting 1 in 4 adults, and death rates are predicted to rise inexorably. The progressive form …

Liver cell types derived from induced pluripotent stem cells (iPSCs) share the potential to
investigate development, toxicity, as well as genetic and infectious disease in ways currently …

Although the currently available pharmacological assays can cure most pathological
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …

Liver cancer and disease are among the most socially challenging global health concerns.
Although organ transplantation, surgical resection and anticancer drugs are the main …

Cell culture is one of the most core and fundamental techniques employed in the fields of
biology and medicine. At present, although the two‐dimensional cell culture method is …

The nicotinamide adenine dinucleotide phosphate hydrogen oxidase (NADPH oxidase or
NOX) plays a critical role in the inflammatory response and fibrosis in several organs such …

Liver organoids represent emerging human-relevant in vitro liver models that have a wide
range of biomedical applications in basic medical studies and preclinical drug discovery …

The liver is a key production and processing site that is essential for health. Liver dysfunction
can result in both systemic and liver-specific diseases. To combat these diseases, genetic …