The role of inflammation in cardiovascular disease (CVD) is now widely accepted. Immune
cells, including T cells, are influenced by inflammatory signals and contribute to the onset …

Dyslipidemia is a main driver of cardiovascular diseases. The ability of macrophages to
scavenge excess lipids implicate them as mediators in this process and understanding the …

Circular RNAs (circRNAs) are involved in many physiological functions. Whether circulating
circRNAs serve as markers for coronary artery disease (CAD) is unknown. Seven CAD …

Aims Chronic kidney disease (CKD) is widely prevalent and independently increases
cardiovascular risk. Cardiovascular risk prediction tools derived in the general population …

Accumulating evidence indicates that macrophages reshape their cholesterol metabolism in
response to pathogens to support host defense. Intervention of host cholesterol homeostasis …

Patients with heart failure (HF) and coronary artery disease (CAD) have a high risk for
cardiovascular (CV) events including HF hospitalization, stroke, myocardial infarction (MI) …

Background: Statins are the most widely used lipid-lowering agents for patients with
hyperlipidemia. However, interindividual variations in efficacy and risk of adverse drug …

This study aimed to assess the association of the tribbles pseudokinase 1 (TRIB1) and
transcriptional repressor GATA binding 1 (TRPS1) single nucleotide polymorphisms (SNPs) …

Background “Quantile-dependent expressivity” occurs when the effect size of a genetic
variant depends upon whether the phenotype (eg cholesterol) is high or low relative to its …

Abstract Aim The long noncoding RNAs (lncRNAs) have gradually been reported to be an
important class of RNAs with pivotal roles in the development and progression of myocardial …