No-reflow phenomenon: pathophysiology, diagnosis, prevention, and treatment. A review of the current literature and future perspectives

G Galasso, S Schiekofer, C D'Anna, GD Gioia… - …, 2014 - journals.sagepub.com
No-reflow is responsible for 40% of the primary percutaneous coronary intervention without
complete myocardial reperfusion despite successful reopening of the infarct-related artery …

Reperfusion therapy—What's with the obstructed, leaky and broken capillaries?

DN Granger, PR Kvietys - Pathophysiology, 2017 - Elsevier
Microvascular dysfunction is well established as an early and rate-determining factor in the
injury response of tissues to ischemia and reperfusion (I/R). Severe endothelial cell …

Predictive value of admission platelet volume indices for in-hospital major adverse cardiovascular events in acute ST-segment elevation myocardial infarction

T Celik, MG Kaya, M Akpek, O Gunebakmaz… - …, 2015 - journals.sagepub.com
Although mean platelet volume (MPV) is an independent correlate of impaired angiographic
reperfusion and 6-month mortality in ST-segment elevation myocardial infarction (STEMI) …

The non-HDL-C/HDL-C ratio is a strong and independent predictor of the no-reflow phenomenon in patients with ST-elevation myocardial infarction

K Toprak, M Kaplangoray, S Akyol, M İnanır… - Acta …, 2024 - Taylor & Francis
Background No-reflow (NR) is the inability to achieve adequate myocardial perfusion
despite successful restoration of attegrade blood flow in the infarct-related artery after …

Conditioning the whole heart—not just the cardiomyocyte

RM Bell, DM Yellon - Journal of molecular and cellular cardiology, 2012 - Elsevier
Conditioning, the recruitment of endogenous cytoprotective pathways that protect the
myocardium against injurious ischaemia/reperfusion injury, has developed into a range of …

[PDF][PDF] 冠脉内逆向应用重组人尿激酶原溶栓联合PCI 对急性ST 段抬高型心肌梗死患者预后的临床研究

陈晓敏, 葛广豪, 曹华, 张立, 刘化进, 王宏伟… - 临床心血管病 …, 2022 - en.whuhzzs.com
目的: 探讨冠状动脉(冠脉) 内逆向应用重组人尿激酶原联合经皮冠脉介入治疗(PCI) 对ST
段抬高型心肌梗死(STEMI) 患者预后的影响. 方法: 选择心内科行急诊PCI 的STEMI 患者120 例 …

Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials

EP Navarese, A Buffon, F Andreotti, PA Gurbel… - Atherosclerosis, 2012 - Elsevier
AIMS: Adjunctive therapy with adenosine has been shown to improve coronary flow in
patients with acute coronary syndromes (ACS); it is unclear, however, whether adenosine …

Update in pharmacological management of coronary no-reflow phenomenon

P Salinas, S Jimenez-Valero, R Moreno… - … Agents in Medicinal …, 2012 - ingentaconnect.com
The no-reflow phenomenon (NRP) is defined as the lack of adequate myocardial tissue
perfusion despite a patent epicardial coronary artery. The incidence of NRP varies between …

Incidence, predictors, and prognosis of coronary slow-flow and no-reflow phenomenon in patients with chronic total occlusion who underwent percutaneous coronary …

Y Wang, H Zhao, C Wang, X Zhang, J Tao… - … and Clinical Risk …, 2020 - Taylor & Francis
Background The incidence and prognosis of coronary slow-flow (CSF) and no-reflow
phenomenon (NRP) in patients with coronary chronic total occlusion (CTO) who underwent …

Reduction of no-reflow and reperfusion injury with the synthetic 17β-aminoestrogen compound Prolame is associated with PI3K/Akt/eNOS signaling cascade

S Hernández-Reséndiz, C Palma-Flores… - Basic research in …, 2015 - Springer
A high proportion of primary percutaneous coronary interventions performed in the setting of
acute myocardial infarction, concur with inadequate myocardial perfusion at the …