Applications of genomics to slow the spread of multidrug‐resistant Neisseria gonorrhoeae

TD Mortimer, YH Grad - Annals of the New York Academy of …, 2019 - Wiley Online Library
Infections with Neisseria gonorrhoeae, a sexually transmitted pathogen that causes
urethritis, cervicitis, and more severe complications, are increasing. Gonorrhea is typically …

The gonococcal transcriptome during infection of the lower genital tract in women

R McClure, K Nudel, P Massari, B Tjaden, X Su… - PloS one, 2015 - journals.plos.org
Gonorrhea is a highly prevalent disease resulting in significant morbidity worldwide, with an
estimated 106 cases reported annually. Neisseria gonorrhoeae, the causative agent of …

An account of evolutionary specialization: the AbcR small RNAs in the Rhizobiales

LM Sheehan, CC Caswell - Molecular microbiology, 2018 - Wiley Online Library
Summary The AbcR small RNAs (sRNAs) are a fascinating example of two highly conserved
sRNAs that differ tremendously at the functional level among organisms. From their …

Transcriptome analysis of Neisseria gonorrhoeae during natural infection reveals differential expression of antibiotic resistance determinants between men and …

K Nudel, R McClure, M Moreau, E Briars, AJ Abrams… - Msphere, 2018 - Am Soc Microbiol
Neisseria gonorrhoeae is a bacterial pathogen responsible for the sexually transmitted
infection gonorrhea. Emergence of antimicrobial resistance (AMR) of N. gonorrhoeae …

Comprehensive identification of meningococcal genes and small noncoding RNAs required for host cell colonization

E Capel, AL Zomer, T Nussbaumer, C Bole, B Izac… - MBio, 2016 - Am Soc Microbiol
Neisseria meningitidis is a leading cause of bacterial meningitis and septicemia, affecting
infants and adults worldwide. N. meningitidis is also a common inhabitant of the human …

Global network analysis of Neisseria gonorrhoeae identifies coordination between pathways, processes, and regulators expressed during human infection

R McClure, A Sunkavalli, PM Balzano, P Massari… - Msystems, 2020 - Am Soc Microbiol
Neisseria gonorrhoeae is a Gram-negative diplococcus that is responsible for the sexually
transmitted infection gonorrhea, a high-morbidity disease in the United States and …

A preliminary study of the mechanism of nitrate-stimulated remarkable increase of rifamycin production in Amycolatopsis mediterranei U32 by RNA-seq

ZH Shao, SX Ren, XQ Liu, J Xu, H Yan, GP Zhao… - Microbial cell …, 2015 - Springer
Background Rifamycin is an important antibiotic for the treatment of infectious disease
caused by Mycobacteria tuberculosis. It was found that in Amycolatopsis mediterranei U32 …

Genome-wide identification of Azospirillum brasilense Sp245 small RNAs responsive to nitrogen starvation and likely involvement in plant-microbe interactions

V Koul, D Srivastava, PP Singh, M Kochar - BMC genomics, 2020 - Springer
Abstract Background Small RNAs (sRNAs) are non-coding RNAs known to regulate various
biological functions such as stress adaptation, metabolism, virulence as well as …

Genome-wide identification and characterization of small RNAs in Rhodobacter capsulatus and identification of small RNAs affected by loss of the response regulator …

MP Grüll, L Peña-Castillo, ME Mulligan, AS Lang - RNA biology, 2017 - Taylor & Francis
Small non-coding RNAs (sRNAs) are involved in the control of numerous cellular processes
through various regulatory mechanisms, and in the past decade many studies have …

Genome-Wide Discovery of Putative sRNAs in Paracoccus denitrificans Expressed under Nitrous Oxide Emitting Conditions

H Gaimster, L Chalklen, M Alston, JT Munnoch… - Frontiers in …, 2016 - frontiersin.org
Nitrous oxide (N2O) is a stable, ozone depleting greenhouse gas. Emissions of N2O into the
atmosphere continue to rise, primarily due to the use of nitrogen-containing fertilizers by soil …