Colorectal cancer (CRC) is one of the most common malignancies worldwide. China,
Europe and northern America account for more than half of the new CRC cases and …

Epidemiologic data indicate a significant increase in the incidence of colorectal cancer in
younger populations in the past three decades. Moreover, recent evidence also …

The incidence of early-onset colorectal—ie, colorectal cancer cancer diagnosed in patients
under the age of 50 years—has been increasing around the world. This Series paper …

Background & Aims Patients with early-onset colorectal cancer (eoCRC) are managed
according to guidelines that are not age-specific. A multidisciplinary international group …

The increasing cancer morbidity and mortality requires the development of high-efficiency
and low-toxicity anticancer approaches. In recent years, photodynamic therapy (PDT) has …

Colorectal cancer (CRC) is a leading cause of cancer morbidity and mortality worldwide.
The etiology and pathogenesis of CRC remain unclear. A growing body of evidence …

Background The beneficial role of gut microbiota and bacterial metabolites, including short-
chain fatty acids (SCFAs), is well recognized, although the available literature around their …

Incidence of early-onset colorectal cancer (EOCRC), defined by a diagnosed age under 50
years, is increasing, but its heterogeneous etiologies that differ from general CRC remain …

Chemoprevention is one of the ways to fight colorectal cancer, which is a huge challenge in
oncology. Numerous pieces of evidence indicate that chronic inflammation in the course of …

Simple Summary In this review, the authors will discuss the highlights of early onset colon
cancer (EOCRC), an increasing but still unclear phenomenon. Indeed, the risk factors are …