Progesterone as an anti-inflammatory drug and immunomodulator: new aspects in hormonal regulation of the inflammation

TA Fedotcheva, NI Fedotcheva, NL Shimanovsky - Biomolecules, 2022 - mdpi.com
The specific regulation of inflammatory processes by steroid hormones has been actively
studied in recent years, especially by progesterone (P4) and progestins. The mechanisms of …

Immune alterations in recurrent implantation failure

N Mukherjee, R Sharma, D Modi - American Journal of …, 2023 - Wiley Online Library
A failure to achieve pregnancy after three or more embryo transfer cycles with high‐quality
blastocysts is referred to as recurrent implantation failure (RIF). RIF can be due to altered …

Characterization of the endometrial microbiome in patients with recurrent implantation failure

FM Lozano, B Lledó, R Morales, A Cascales, M Hortal… - Microorganisms, 2023 - mdpi.com
An abnormal endometrial microbiota has been associated with implantation failure;
therefore, it may be important to evaluate it in order to improve reproductive outcomes in …

Cycle biodynamics of women's microbiome in the urinary and reproductive systems

O Grobeisen-Duque, CD Mora-Vargas… - Journal of clinical …, 2023 - mdpi.com
The genitourinary microbiome plays a crucial role in the establishment and maintenance of
urinary and reproductive health in women throughout their lives. Particularly during the …

Role of inflammatory factors in the etiology and treatment of recurrent implantation failure

Q Wang, Y Sun, R Fan, M Wang, C Ren, A Jiang… - Reproductive …, 2022 - Elsevier
Recurrent implantation failure (RIF) is characterized by the absence of implantation after
high-grade embryos are transferred to the endometrium by at least three in vitro fertilization …

Endometrial proteomic profile of patients with repeated implantation failure

J Yang, L Wang, J Ma, L Diao, J Chen… - Frontiers in …, 2023 - frontiersin.org
Introduction Successful embryo implantation, is the initiating step of pregnancy, relies on not
only the high quality of the embryo but also the synergistic development of a healthy …

Seasonal Serum 25 (OH) Vitamin D Level and Reproductive or Immune Markers in Reproductive-Aged Women with Infertility: A Cross-Sectional Observational Study …

K Ota, J Mitsui, S Katsumata, Y Takayanagi, Y Nako… - Nutrients, 2023 - mdpi.com
Several studies have reported that vitamin D may modify human reproductive functions;
however, the results are conflicting. We aimed to comprehensively evaluate serum vitamin D …

Pro- and anti-inflammatory cytokines and growth factors in patients undergoing in vitro fertilization procedure treated with prednisone

K Piekarska, M Dratwa, P Radwan, M Radwan… - Frontiers in …, 2023 - frontiersin.org
Embryo implantation is a key moment in pregnancy. Abnormal production of pro-and anti-
inflammatory cytokines, their receptors and other immune factors may result in embryo …

Polymorphic variants of genes encoding angiogenesis-related factors in infertile women with recurrent implantation failure

AE Mrozikiewicz, G Kurzawińska, M Ożarowski… - International Journal of …, 2023 - mdpi.com
Recurrent implantation failure (RIF) is a global health issue affecting a significant number of
infertile women who undergo in vitro fertilization (IVF) cycles. Extensive vasculogenesis and …

Recurrent implantation failure: bioinformatic discovery of biomarkers and identification of metabolic subtypes

Y Fan, C Shi, N Huang, F Fang, L Tian… - International Journal of …, 2023 - mdpi.com
Recurrent implantation failure (RIF) is a challenging scenario from different standpoints. This
study aimed to investigate its correlation with the endometrial metabolic characteristics …