MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …

Extracellular vesicles (EVs) are produced by diverse eukaryotic and prokaryotic cells. They
have prominent roles in the modulation of cell-cell communication, inflammation versus …

Hematopoiesis is a complex process in which hematopoietic stem cells are differentiated
into all mature blood cells (red blood cells, white blood cells, and platelets). Different …

MicroRNAs, as non-coding transcripts, modulate gene expression through RNA silencing
under normal physiological conditions. Their aberrant expression has strongly associated …

Hematopoietic stem cells (HSCs) are the only cell population that possesses both a self-
renewing capacity and multipotency, and can give rise to all lineages of blood cells …

Abstract Owing to Karl Landsteiner's discovery of blood groups, blood transfusions became
safe cellular therapies in the early 1900s. Since then, cellular therapy made great advances …

Pancreatic cancer constitutes the fourth most frequent cause of death due to malignancy in
the US. Despite the new therapeutic modalities, the management of pancreatic ductal …

Stem cells' self-renewal and multi-lineage differentiation are regulated by a complex network
consisting of signaling factors, chromatin regulators, transcription factors, and non-coding …

Mesenchymal stem cells (MSCs) are crucial cells that play an essential role in the
maintenance, self‐renewal, and proliferation of hematopoietic stem cells (HSCs) and …

Self-renewal and differentiation into diverse cells are two main characteristics of stem cells.
These cells have important roles in development and homeostasis of different tissues and …