Our understanding of depression and its treatment has advanced with the advent of
ketamine as a rapid-acting antidepressant and the development and refinement of tools …

Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that
allows neurons to communicate and change their connections as a function of past …

Importance More than half of patients with alcohol use disorder who receive inpatient
withdrawal treatment relapse within weeks of discharge, hampering subsequent uptake and …

In modern society, depression is one of the most common mental illness; however, its
pathophysiology is not yet fully understood. A great body of evidence suggests that …

Clozapine is superior to other antipsychotics as a therapy for treatment-resistant
schizophrenia and schizoaffective disorder with increased risk of suicidal behavior. This …

Background Electroconvulsive therapy (ECT) is an effective neuromodulatory treatment for
major depressive disorder (MDD), especially for cases resistant to antidepressant drugs …

Ever since the dawn of antiquity, people have strived to improve their cognitive abilities.
From the advent of the wheel to the development of artificial intelligence, technology has …

The etiology of psychiatric disorders remains largely unknown. The exploration of the
neurobiological mechanisms of mental illness helps improve diagnostic efficacy and …

The separation distress hypothesis of depression, formulated in 2009, offered an affective
neuroscience perspective on our most common and costly mental health condition, as an …

Autism spectrum disorder (ASD) and intellectual disability (ID) are heterogenous and
prevalent conditions which may occur in isolation or as a co-morbidity. Psychiatric co …