Nitric oxide (NO) is a powerful biological mediator provided with a number of activities of
relevance for the prevention of thrombosis, like vasodilation, inhibition of platelet adhesion …

High level of circulating red cell distribution width (RDW) and neutrophil/lymphocyte (N/L)
ratio may reflect ongoing vascular inflammation and play an important role in …

The utility of β-blockers in the treatment of hypertension has created much speculation as to
their efficacy in patients with comorbid conditions, and there are concerns regarding their …

Objective—dl-Nebivolol, a selective β1-adrenergic receptor antagonist, besides its
hypotensive activity exerts vasodilatory and platelet inhibitory effects in vitro by a mechanism …

Endothelin-1 (ET-1) plays a major role in the pathophysiology of hypertension and its
associated cardiovascular risk. We tested the hypothesis that chronic nebivolol treatment …

Asymmetric dimethylarginine (ADMA) is an endogenous and competitive inhibitor of nitric
oxide synthase. Plasma level of ADMA is elevated in patients with hypertension. In these …

Резюме В оглядовій статті узагальнено результати експериментальних і клінічних
досліджень, що стосуються вивчення причин і механізмів розвитку, діагностики …

Organ culture of blood vessels provides a useful technique to investigate long-term effects of
drugs because tissue architecture and function are well preserved. Various growth factors …

Objective This study examined the combined effect of nebivolol (NEB) and
hydrochlorothiazide (HCTZ) on cardiovascular function in spontaneously hypertensive rats …

Hypertension is a common disease, and hypertensive patients are at increased risk of
cardiovascular events. The prevalence and socioeconomic burden of hypertension in the …