Epigenetics has achieved a profound impact in the biomedical field, providing new
experimental opportunities and innovative therapeutic strategies to face a plethora of …

Beckwith–Wiedemann syndrome (BWS) is a genetic overgrowth and cancer predisposition
syndrome, associated with both benign and malignant adrenal findings. Literature review …

Widespread use of the next-generation sequencing (NGS) technologies revealed that a
significant percentage of tumors in children develop as a part of monogenic hereditary …

Cancer predisposition syndromes (CPS) are known to cause a variety of sarcomas.
Consideration for genetic testing in patients with a strong family history of cancer, multiple …

Abstract Background The Wnt/β‐catenin pathway plays a central role in the pathogenesis of
most hepatoblastomas (HBs), that is, up to 60–80% carry activating CTNNB1 mutations. HBs …

Abstract Children with Beckwith-Wiedemann Syndrome (BWS) and Isolated
Hemihypertrophy (IHH) are at an increased risk for developing tumors. Tumor screening in …

To designate the probable most important differentially expressed genes and genetic
pathways in Wilms tumor and assess their expression and diagnostic potential by RT-PCR …

This study reports a case of hepatoblastoma with onset at 30-weeks' gestation and rapid
growth rate. The postnatal enhanced CT confirmed an intrahepatic mass with a size of 8.5 …

Beckwith‐Wiedemann syndrome (BWS) is a genomic imprinting disorder, characterized by
macroglossia, abdominal wall defects, lateralized overgrowth, and predisposition to …

BACKGROUND: Beckwith-Wiedemann syndrome (BWS) is the most common congenital
overgrowth disorder with an incidence of approximately 1 in 10,000 live births. The condition …