Molecular regulation of follicle-stimulating hormone synthesis, secretion and action

N Das, TR Kumar - Journal of molecular endocrinology, 2018 - jme.bioscientifica.com
Follicle-stimulating hormone (FSH) plays fundamental roles in male and female fertility. FSH
is a heterodimeric glycoprotein expressed by gonadotrophs in the anterior pituitary. The …

A new pathway in the control of the initiation of puberty: the MKRN3 gene

AP Abreu, DB Macedo, VN Brito… - Journal of …, 2015 - jme.bioscientifica.com
Follicle-stimulating hormone (FSH) plays fundamental roles in male and female fertility. FSH
is a heterodimeric glycoprotein expressed by gonadotrophs in the anterior pituitary. The …

Prospects for FSH treatment of male infertility

M Simoni, G Brigante, V Rochira… - The Journal of …, 2020 - academic.oup.com
Context Despite the new opportunities provided by assisted reproductive technology (ART),
male infertility treatment is far from being optimized. One possibility, based on …

Genome-wide association study reveals candidate genes for litter size traits in pelibuey sheep

W Hernández-Montiel, MA Martínez-Núñez… - Animals, 2020 - mdpi.com
Simple Summary Reproductive traits are economically important in the livestock industry,
and this is of greater relevance when it comes to indigenous animals, since their study …

Follicle-stimulating hormone glycobiology

GR Bousfield, DJ Harvey - Endocrinology, 2019 - academic.oup.com
FSH glycosylation varies in two functionally important aspects: microheterogeneity, resulting
from oligosaccharide structure variation, and macroheterogeneity, arising from partial FSH β …

[HTML][HTML] New human follitropin preparations: how glycan structural differences may affect biochemical and biological function and clinical effect

JA Dias, A Ulloa-Aguirre - Frontiers in Endocrinology, 2021 - frontiersin.org
It is well accepted that pituitary follitropin is secreted into the circulation as a mixture of
variants, which differ not in primary structure but rather at the level of glycosylation. These …

[HTML][HTML] In vivo and in vitro impact of carbohydrate variation on human follicle-stimulating hormone function

GR Bousfield, JV May, JS Davis, JA Dias… - Frontiers in …, 2018 - frontiersin.org
Human follicle-stimulating hormone (FSH) exhibits both macro-and microheterogeneity in its
carbohydrate moieties. Macroheterogeneity results in three physiologically relevant FSHβ …

RNA-seq analysis identifies age-dependent changes in expression of mRNAs-encoding N-glycosylation pathway enzymes in mouse gonadotropes

R McDonald, M Larsen, Z Liu, S Southekal… - Molecular and Cellular …, 2023 - Elsevier
Follicle-stimulating hormone (FSH) is a glycoprotein that is assembled as a heterodimer of
α/β subunits in gonadotropes. Each subunit contains two N-glycan chains. Our previous in …

Effect of LHCGR and FSHR gene polymorphisms on fertility traits and milk yield of cross-bred dairy cows in Sri Lanka

DI Abeygunawardana, RMSBK Ranasinghe… - Animal …, 2023 - Taylor & Francis
Single nucleotide polymorphism (SNP) analysis of fertility genes will be useful in improving
the genetic potential of dairy cows. A population of 142 cross-bred dairy cows was screened …

The solute carrier family 7 member 11 (SLC7A11) is regulated by LH/androgen and required for cystine/glutathione homeostasis in mouse Sertoli cells

Z Liu, H Wang, M Larsen, S Gunewardana… - Molecular and cellular …, 2022 - Elsevier
Luteinizing hormone (LH) stimulates testosterone production from Leydig cells. Both LH and
testosterone play important roles in spermatogenesis and male fertility. To identify LH-and …