Abstract Alzheimer's disease (AD), characterized by the β-amyloid protein (Aβ) deposition
and tau hyperphosphorylation, is the most common dementia with uncertain etiology. The …

Iron accumulation has been associated with the etiology and progression of multiple
neurodegenerative diseases (NDDs). The exact role of iron in these diseases is not fully …

Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

Despite loss of grey matter volume and emergence of distinct cognitive deficits in young
adults diagnosed with schizophrenia, current treatments for schizophrenia do not target …

The incidence of neurological diseases, such as Parkinson's disease, Alzheimer's disease
and stroke, is increasing. An increasing number of studies have correlated these diseases …

Since the description of some peculiar symptoms by James Parkinson in 1817, attempts
have been made to define its cause or at least to enlighten the pathology of “Parkinson's …

Serious concerns have recently been raised regarding the association of Fe excess with
neurodegenerative diseases in mammals and nutritional and oxidative disorders in plants …

Ferroptosis and neuroinflammation contribute to the development of Alzheimer's disease
(AD). Isoforsythiaside (IFY) is a phenylethanoid glycoside isolated from the dried fruit of …

Background Brain iron overload is linked to brain deterioration, and cognitive and motor
impairment in neurodegenerative disorders and normal aging. Mutations in the HFE gene …

Qiangji Decoction (QJD), a classic formula, has been widely used to treat brain aging–
related neurodegenerative diseases. However, the mechanisms underlying QJD's …