Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …

Introduction Spinal cord injury (SCI) affects 25,000–50,000 people around the world each
year and there is no cure for SCI patients currently. The primary injury damages spinal cord …

Background Neuroinflammation following spinal cord injury (SCI) results in prolonged
neurological damage and locomotor dysfunction. Polarization of microglia is vital to …

Mitochondria are crucial in sustaining and orchestrating cellular functions. Capitalizing on
this, we explored mitochondrial transplantation as an innovative therapeutic strategy for …

Spinal cord injury (SCI) starts with a mechanical and/or bio-chemical insult, followed by a
secondary phase, leading progressively to severe collapse of the nerve tissue. Compared to …

Background: Insufficient neuronal mitochondrial bioenergetics supply occurs after spinal
cord injury (SCI), leading to neuronal apoptosis and impaired motor function. Previous …

Mitochondrial damage caused by oxidative stress and energy deficiency induced by focal
ischemia and hypoxia are important factors that aggravate diseases. Studies have shown …

Traumatic spinal cord injuries interrupt the connection of all axonal projections with their
neuronal targets below and above the lesion site. This interruption results in either …

Spinal cord injury (SCI) affects hundreds of thousands of people in the United States, and
while some effects of the injury are broadly recognized (deficits to locomotion, fine motor …

Spinal cord injury is an impact-induced disabling condition. A series of pathological changes
after spinal cord injury (SCI) are usually associated with oxidative stress, inflammation, and …