Background: According to some guidelines, white-coat hypertension (WCH) carries little or
no increase of cardiovascular risk in the absence of organ damage (OD), but no data are …

Background. Increased levels of inflammatory biomarkers such as interleukin-6 (IL-6), 10 (IL-
10), 1β (IL-1β), tumor necrosis factor-α (TNF-α) high-sensitivity C-reactive protein (hs-CRP) …

Aim: We evaluated clinic BP levels and the rate of BP control in hypertensive patients
included in observational studies and clinical surveys published between 2005 and 2011 in …

Objective The prevalence of primary aldosteronism in unselected hypertensive patients is
currently unknown. We investigated the frequency of positive screening results for primary …

Arterial hypertension accounts for the largest amount of attributable cardiovascular mortality
worldwide, and risk stratification in hypertensive patients is of crucial importance to manage …

The blood pressure (BP) J-curve debate started in 1979, and we still cannot definitively
answer all the questions. However, available studies of antihypertensive treatment provide …

Outcomes. Extensive data from randomised controlled trials have shown the benefit of
treating hypertension. The target blood pressure (BP) for antihypertensive management is …

The prevalence of diabetes, predominantly of type 2, and the incidence of diabetic
nephropathy have dramatically increased worldwide. Diabetic patients constitute the largest …

Objectives Current guidelines recommend the use of multiple medications for hypertension.
The present study was aimed at determining which combination was optimal to prevent …

BACKGROUND: Chlorthalidone has proven efficacy to reduce cardiovascular morbidity and
mortality, yet it is infrequently used in practice. This study provides a direct comparison of …