1 The mechanisms responsible for sensing hypoxia and initiating hypoxic pulmonary
vasoconstriction (HPV) are unclear. We therefore examined the roles of the mitochondrial …

Oxygen pressure declines from normoxic air-level to the microenvironment of mitochondria
where cytochrome c oxidase (COX) reduces oxygen to water at oxygen levels as low as 0.3 …

Proteomics is a useful analytical approach for investigating crop responses to stress. Recent
remarkable advances in proteomic techniques allow for the identification of a wider range of …

Atherosclerosis is by far the most frequent underlying cause of coronary artery disease,
carotid artery disease and peripheral arterial disease, and is associated with high morbidity …

Owing to the variability of oxygen tension in aquatic, especially the freshwater environment,
oxygen has been a major force in the evolution of fishes. Their long evolutionary history, and …

Environmental contamination is often characterised by a combination of stress factors of
various sources (biological, physical and chemical). The predictability of their joint effects is …

Maladaptive changes in the carotid body (CB) induced by chronic intermittent hypoxia (IH)
account for the pathogenesis of cardiovascular morbidity in patients with sleep-disordered …

HIF-1 is composed of HIF-1α and HIF-1ß protein subunits. HIF-1 is induced by hypoxia and
binds to promoter/enhancer elements and stimulates the transcription of hypoxia-inducible …

The hypoxia-induced membrane depolarization and subsequent constriction of small
resistance pulmonary arteries occurs, in part, via inhibition of vascular smooth muscle cell …

Монография посвящена анализу современных представлений о ведущей роли
митохондрий в сложнейшей системе внутриклеточной и межклеточной сигнализации …