[HTML][HTML] In utero ethanol exposure induces mitochondrial DNA damage and inhibits mtDNA repair in developing brain
N Darbinian, A Darbinyan, N Merabova… - Frontiers in …, 2023 - frontiersin.org
Introduction Mitochondrial dysfunction is postulated to be a central event in fetal alcohol
spectrum disorders (FASD). People with the most severe form of FASD, fetal alcohol …
spectrum disorders (FASD). People with the most severe form of FASD, fetal alcohol …
[HTML][HTML] Biomarkers of Affective Dysregulation Associated with In Utero Exposure to EtOH
N Darbinian, N Merabova, G Tatevosian, M Morrison… - Cells, 2023 - mdpi.com
Introduction: Children with fetal alcohol spectrum disorders (FASD) exhibit behavioral and
affective dysregulation, including hyperactivity and depression. The mechanisms are not …
affective dysregulation, including hyperactivity and depression. The mechanisms are not …
[HTML][HTML] Drosophila CASK regulates brain size and neuronal morphogenesis, providing a genetic model of postnatal microcephaly suitable for drug discovery
JA Tello, L Jiang, Y Zohar, LL Restifo - Neural Development, 2023 - Springer
Background CASK-related neurodevelopmental disorders are untreatable. Affected children
show variable severity, with microcephaly, intellectual disability (ID), and short stature as …
show variable severity, with microcephaly, intellectual disability (ID), and short stature as …
[HTML][HTML] Effects of In Utero EtOH Exposure on 18S Ribosomal RNA Processing: Contribution to Fetal Alcohol Spectrum Disorder
N Darbinian, GL Gallia, A Darbinyan… - International journal of …, 2023 - mdpi.com
Fetal alcohol spectrum disorders (FASD) are leading causes of neurodevelopmental
disability. The mechanisms by which alcohol (EtOH) disrupts fetal brain development are …
disability. The mechanisms by which alcohol (EtOH) disrupts fetal brain development are …
[HTML][HTML] Maternal Blood Lipid Biomarkers of Oligodendrocyte Pathology to Predict Fetal Alcohol Spectrum Disorders
N Darbinian, EC Sparks, A Darbinyan… - Obstetrics and …, 2023 - ncbi.nlm.nih.gov
Methods: Blood samples were collected from two groups of pregnant women: 1) those who
consumed EtOH during pregnancy, and 2) non-EtOH using controls, under an IRB-approved …
consumed EtOH during pregnancy, and 2) non-EtOH using controls, under an IRB-approved …