Targeting white adipose tissue with exercise or bariatric surgery as therapeutic strategies in obesity

F Giolo De Carvalho, LM Sparks - Biology, 2019 - mdpi.com
Adipose tissue is critical to whole-body energy metabolism and has become recognized as
a bona fide endocrine organ rather than an inert lipid reservoir. As such, adipose tissue is …

Exercise Alleviates Aging of Adipose Tissue through Adipokine Regulation

D Jia, H Zhang, T Liu, R Wang - Metabolites, 2024 - mdpi.com
Adipose tissue undergoes changes with aging, leading to increased adiposity, inflammatory
cell infiltration, reduced angiogenesis, heightened oxidative stress, and alterations in its …

[HTML][HTML] Combined effects of voluntary running and liraglutide on glucose homeostasis, fatty acid composition of brown adipose tissue phospholipids, and white …

R Yin, Y Ma, N Zhang, L Yang… - Journal of Physiology …, 2022 - journals.lww.com
There is a potential therapeutic application targeting brown adipose tissue (BAT). Either
voluntary running or liraglutide increases the thermogenesis of BAT in type 2 diabetes …

Endocrine mechanisms connecting exercise to brown adipose tissue metabolism: a human perspective

A Mendez-Gutierrez, FJ Osuna-Prieto… - Current Diabetes …, 2020 - Springer
Abstract Purpose of Review To summarize the state-of-the-art regarding the exercise-
regulated endocrine signals that might modulate brown adipose tissue (BAT) activity and/or …

Proteomic analysis of skeletal muscle and white adipose tissue after aerobic exercise training in high fat diet induced obese mice

TJ Chou, CW Lu, LY Lin, YJ Hsu, CC Huang… - International Journal of …, 2023 - mdpi.com
Obesity is associated with excessive fat accumulation in adipose tissue and other organs,
such as skeletal muscle, whereas aerobic exercise (AE) plays an important role in managing …

Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT)

H Dong, M Qin, P Wang, S Li, X Wang - Adipocyte, 2023 - Taylor & Francis
Exercise is a universally acknowledged and healthy way to reducing body weight. However,
the roles and mechanisms of exercise on metabolism of adipose tissue remain largely …

[HTML][HTML] Dendritic cells in energy balance regulation

A Redondo-Urzainqui, E Hernández-García… - Immunology …, 2023 - Elsevier
Besides their well-known role in initiating adaptive immune responses, several groups have
studied the role of dendritic cells (DCs) in the context of chronic metabolic inflammation …

[HTML][HTML] The blooming intersection of subfatin and metabolic syndrome

S Huang, L Cao, H Cheng, D Li, Y Li… - Reviews in …, 2021 - imrpress.com
Metabolic Syndrome (MS) remains the leading cause of mortality and morbidity globally.
Adipose tissue releases adipokines that play key roles in metabolic and cardio-cerebro …

Exercise training induces depot-specific remodeling of protein secretion in skeletal muscle and adipose tissue of obese male mice

MK Montgomery, W De Nardo… - American Journal of …, 2023 - journals.physiology.org
Acute exercise induces changes in circulating proteins, which are known to alter metabolism
and systemic energy balance. Skeletal muscle is a primary contributor to changes in the …

The expression of brown fat‐associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis

A Alnabulsi, B Cash, Y Hu, L Silina… - … Journal of Cancer, 2019 - Wiley Online Library
Colorectal carcinoma is one of the most common types of malignancy and a leading cause
of cancer related death. The aberrant expression of a brown fat‐like phenotype in cancer …