Lysosomal nanotoxicity: Impact of nanomedicines on lysosomal function

M Uzhytchak, B Smolková, M Lunova, A Frtús… - Advanced Drug Delivery …, 2023 - Elsevier
Although several nanomedicines got clinical approval over the past two decades, the clinical
translation rate is relatively small so far. There are many post-surveillance withdrawals of …

Noncovalent PEGylation of protein and peptide therapeutics

AK Andrianov - Wiley Interdisciplinary Reviews: Nanomedicine …, 2023 - Wiley Online Library
Clinical applications of protein therapeutics—an advanced generation of drugs
characterized by high biological specificity—are rapidly expanding. However, their …

Polyphosphazenes—A promising candidate for Drug Delivery, Bioimaging, and tissue Engineering: a review

P Ilayaperumal, P Chelladurai, K Vairan… - Macromolecular …, 2023 - Wiley Online Library
Synthetic polymer materials have been surged to the forefront of research in the fields of
tissue engineering, drug delivery, and biomonitoring in recent years. Biodegradable …

[HTML][HTML] A review on functional applications of polyphosphazenes as multipurpose material for lithium-ion batteries

Z Zhao, Z Xu, J Chen, M Zhong, J Wang… - Journal of Energy …, 2024 - Elsevier
Polyphosphazenes, which are inorganic-organic hybrid polymers with Pdouble bondN as
the skeleton, are well-known for their unique physicochemical properties stemming from …

Phosphorus and Silicon‐Based Macromolecules as Degradable Biomedical Polymers

S Haudum, P Strasser… - Macromolecular …, 2023 - Wiley Online Library
Synthetic polymers are indispensable in biomedical applications because they can be
fabricated with consistent and reproducible properties, facile scalability, and customizable …

Comparison between nanoparticle encapsulation and surface loading for lysosomal enzyme replacement therapy

E Muntimadugu, M Silva-Abreu, G Vives… - International journal of …, 2022 - mdpi.com
Poly (lactide-co-glycolide)(PLGA) nanoparticles (NPs) enhance the delivery of therapeutic
enzymes for replacement therapy of lysosomal storage disorders. Previous studies …

Recent Trends in the Development of Polyphosphazenes for Bio-applications

F Chen, OR Teniola, KS Ogueri… - … and Translational Medicine, 2023 - Springer
Recent advances in biomedicine necessitate the critical and systematic review of current
trends in the development and modification of biomaterials for biomedical applications …

4-Methylumbelliferone-Functionalized Polyphosphazene and Its Assembly into Biocompatible Fluorinated Nanocoatings with Selective Antiproliferative Activity

HD Tagad, J Brito, A Marin, C Buckley, H Wang… - …, 2023 - ACS Publications
Advanced multifunctional biomaterials are increasingly relying on clinically dictated patterns
of selectivity against various biological targets. Integration of these frequently conflicting …

Nano-assembly of quisinostat and biodegradable macromolecular carrier results in supramolecular complexes with slow-release capabilities

A Chowdhury, A Marin, DJ Weber, AK Andrianov - Pharmaceutics, 2021 - mdpi.com
Self-assembly of ionically charged small molecule drugs with water-soluble biodegradable
polyelectrolytes into nano-scale complexes can potentially offer a novel and attractive …

[引用][C] Delivery of protein therapeutics and vaccines using their multivalent complexes with synthetic polyelectrolytes

AK Andrianov - 2024 - Elsevier