The tumor microenvironment in esophageal cancer

EW Lin, TA Karakasheva, PD Hicks, AJ Bass… - Oncogene, 2016 - nature.com
Esophageal cancer is a deadly disease, ranking sixth among all cancers in mortality.
Despite incremental advances in diagnostics and therapeutics, esophageal cancer still …

The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer

V Hannelien, G Karel, S Sofie - … et Biophysica Acta (BBA)-Reviews on …, 2012 - Elsevier
Chronic inflammation may increase the risk to develop cancer, for instance esophagitis or
gastritis may lead to development of esophageal or gastric cancer, respectively. The key …

Stirring the porphyrin alphabet soup—functionalization reactions for porphyrins

MO Senge - Chemical Communications, 2011 - pubs.rsc.org
Advances in the synthesis of unsymmetrically meso substituted porphyrins are based on the
development of new total syntheses and porphyrin functionalization methods. These …

Cross-talk between the microbiome and chronic inflammation in esophageal cancer: potential driver of oncogenesis

T Sharma, A Gupta, R Chauhan, AA Bhat… - Cancer and Metastasis …, 2022 - Springer
Esophageal cancer (EC) is frequently considered a lethal malignancy and is often identified
at a later stage. It is one of the major causes of cancer-related deaths globally. The …

IL-6 expression regulates tumorigenicity and correlates with prognosis in bladder cancer

MF Chen, PY Lin, CF Wu, WC Chen, CT Wu - PloS one, 2013 - journals.plos.org
Identification of potential tumor markers will help stratify and identify a tumor's malignant
potential and its response to specific therapies. IL-6 has been reported to be a predictor in …

Tumour extracellular vesicles induce neutrophil extracellular traps to promote lymph node metastasis

X Su, A Brassard, A Bartolomucci… - Journal of …, 2023 - Wiley Online Library
Lymph nodes (LNs) are frequently the first sites of metastasis. Currently, the only prognostic
LN assessment is determining metastatic status. However, there is evidence suggesting that …

Novel immune-related ferroptosis signature in esophageal cancer: An informatics exploration of biological processes related to the TMEM161B-AS1/hsa-miR-27a-3p …

M Lu, J Li, X Fan, F Xie, J Fan, Y Xiong - Frontiers in Genetics, 2022 - frontiersin.org
Background: Considering the role of immunity and ferroptosis in the invasion, proliferation
and treatment of cancer, it is of interest to construct a model of prognostic-related differential …

Actin‐Binding Proteins as Potential Biomarkers for Chronic Inflammation‐Induced Cancer Diagnosis and Therapy

YG Zhang, JT Niu, HW Wu, XL Si… - Analytical Cellular …, 2021 - Wiley Online Library
Actin‐binding proteins (ABPs), by interacting with actin, regulate the polymerization,
depolymerization, bundling, and cross‐linking of actin filaments, directly or indirectly …

1α, 25-dihydroxyvitamin D3 inhibits esophageal squamous cell carcinoma progression by reducing IL6 signaling

PT Chen, CC Hsieh, CT Wu, TC Yen, PY Lin… - Molecular cancer …, 2015 - AACR
The aim of this study was to highlight the role of 1α, 25-dihydroxyvitamin D3 (calcitriol) in
esophageal squamous cell carcinoma (SCC). The human esophageal SCC cell lines …

Lactobacillus sp. Facilitate the Repair of DNA Damage Caused by Bile-Induced Reactive Oxygen Species in Experimental Models of Gastroesophageal Reflux …

JN Bernard, V Chinnaiyan, J Almeda… - Antioxidants, 2023 - mdpi.com
Gastroesophageal reflux disease (GERD) leads to the accumulation of bile-induced reactive
oxygen species and oxidative stress in esophageal tissues, causing inflammation and DNA …