In tumor therapeutics, the transition from conventional cytotoxic drugs to targeted molecular
therapies, such as those targeting receptor tyrosine kinases, has been pivotal. Despite this …

Human malignant brain tumors such as gliomas are devastating due to the induction of
cerebral edema and neurodegeneration. A major contributor to glioma-induced …

Reactive oxygen species (ROS) are essential for biological processes like cell signaling and
chemical processes like organic oxidation. Moreover, the sufficient generation of ROS plays …

The aggressive and incurable diffuse gliomas constitute 80% of malignant brain tumors, and
patients succumb to recurrent surgeries and drug resistance. Epidemiological research …

Glioblastoma (GB) is a tumor of the central nervous system characterized by high
proliferation and invasiveness. The standard treatment for GB includes radiotherapy and …

Background Spinal cord glioma (SCG) is considered an orphan disease that lacks effective
treatment options with margins that are surgically inaccessible and an overall paucity of …

Proteomics has been little used for the identification of novel prognostic and/or therapeutic
markers in isocitrate dehydrogenase (IDH)‐wildtype glioblastoma (GB). In this study, we …

Oxidative stress is caused by an imbalance between the production of reactive oxygen
species (ROS) and the body's ability to counteract their harmful effects, playing a key role in …

Glioblastoma multiforme (GBM) is regarded as the most aggressive form of brain tumor
delineated by high cellular heterogeneity; it is resistant to conventional therapeutic …

Glioma is a devastating type of brain tumor with high morbidity and mortality rates. Despite
current treatment options, the prognosis for glioma patients remains poor. Metabolic …