Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: present and future

SR Li, QW Man, X Gao, H Lin, J Wang… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐bilayer membrane structures secreted by most cell
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …

Harnessing the therapeutic potential of extracellular vesicles for biomedical applications using multifunctional magnetic nanomaterials

L Yang, KD Patel, C Rathnam, R Thangam, Y Hou… - Small, 2022 - Wiley Online Library
Extracellular vesicles (eg, exosomes) carrying various biomolecules (eg, proteins, lipids,
and nucleic acids) have rapidly emerged as promising platforms for many biomedical …

Simultaneous detection of tumor derived exosomal protein–microRNA pairs with an Exo-PROS biosensor for cancer diagnosis

CC Hsu, Y Yang, E Kannisto, X Zeng, G Yu… - ACS …, 2023 - ACS Publications
Tumor derived exosomes (TEXs) have emerged as promising biomarkers for cancer liquid
biopsy. Conventional methods (such as ELISA and qRT-PCR) and emerging biosensing …

Surface plasmon coupling electrochemiluminescence immunosensor based on polymer dots and AuNPs for ultrasensitive detection of pancreatic cancer exosomes

H Xiong, Z Huang, Q Lin, B Yang, F Yan, B Liu… - Analytical …, 2021 - ACS Publications
Polymer dots (Pdots) have become attractive electrochemiluminescence (ECL)
luminophores due to their facile synthesis, easy modification, and stable electrochemical …

[HTML][HTML] Therapeutic strategy of mesenchymal-stem-cell-derived extracellular vesicles as regenerative medicine

Y Matsuzaka, R Yashiro - International Journal of Molecular Sciences, 2022 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer membrane particles that play critical roles in
intracellular communication through EV-encapsulated informative content, including …

[HTML][HTML] The biogenesis and secretion of exosomes and multivesicular bodies (MVBs): Intercellular shuttles and implications in human diseases

M Xu, J Ji, D Jin, Y Wu, T Wu, R Lin, S Zhu, F Jiang… - Genes & …, 2023 - Elsevier
Exosomes carry and transmit signaling molecules used for intercellular communication. The
generation and secretion of exosomes is a multistep interlocking process that allows …

Aptamer-initiated catalytic hairpin assembly fluorescence assay for universal, sensitive exosome detection

J Zhou, Q Lin, Z Huang, H Xiong, B Yang… - Analytical …, 2022 - ACS Publications
Cancer-cell-derived exosomes are regarded as noninvasive biomarkers for early cancer
diagnosis because of their critical roles in intercellular communication and molecular …

[HTML][HTML] Multiplexed profiling of extracellular vesicles for biomarker development

C Jiang, Y Fu, G Liu, B Shu, J Davis, GK Tofaris - Nano-micro letters, 2022 - Springer
Extracellular vesicles (EVs) are cell-derived membranous particles that play a crucial role in
molecular trafficking, intercellular transport and the egress of unwanted proteins. They have …

[HTML][HTML] Tumor-derived small extracellular vesicles: potential roles and mechanism in glioma

X Guo, R Sui, H Piao - Journal of Nanobiotechnology, 2022 - Springer
Small extracellular vesicles (SEVs) are extracellular vesicles containing DNA, RNA, and
proteins and are involved in intercellular communication and function, playing an essential …

A Magnetically Driven Tandem Chip Enables Rapid Isolation and Multiplexed Profiling of Extracellular Vesicles

G Zhang, Y Wang, W Zhou, Y Lei, J Lu… - Angewandte …, 2023 - Wiley Online Library
The protein phenotypes of extracellular vesicles (EVs) have emerged as promising
biomarkers for cancer diagnosis and treatment monitoring. However, the technical …