Identification of an ex vivo inhibitor of the schizophrenia biomarker Ndel1 by high throughput screening

JV Nani, C Coelho, WY Oyadomari, TC Santiago… - Biochemical …, 2023 - Elsevier
Ndel1 oligopeptidase activity shows promise as a potential biomarker for diagnosing
schizophrenia (SCZ) and monitoring early-stage pharmacotherapy. Ndel1 plays a pivotal …

TNF-α blockage prevents late neurological consequences of Zika virus infection in mice

RR Christoff, IL Liesner, D Gavino-Leopoldino… - Behavioural Brain …, 2024 - Elsevier
Zika virus (ZIKV) is a neurotropic Orthoflavivirus that causes a myriad of neurological
manifestations in newborns exposed in uterus. Despite the devastating consequences of …

Infection by zika virus increase angiotensin I-converting enzyme activity in mouse brain

WY Oyadomari, RR Christoff, JV Nani, T Rabello… - Biochimie, 2024 - Elsevier
Congenital zika virus syndrome (CZS) has become a significant worldwide concern since
the sudden rise of microcephaly related to zika virus (ZIKV) in Brazil. Primarily transmitted by …