Gamma-glutamyl transferase (GGT) is a ubiquitous cell surface enzyme that cleaves
extracellular glutathione (G-SH) or other gamma-glutamyl compounds. GGT serves to …

Alcohol is a hepatotoxin that is commonly consumed worldwide and is associated with a
spectrum of liver injury including simple steatosis or fatty liver, alcoholic hepatitis, fibrosis …

Alcoholic liver disease (ALD) is the most prevalent cause of advanced liver disease in
Europe. However, there has been limited research investment into ALD despite its …

The susceptibility for various diseases as well as the response to treatments differ
considerably between men and women. As a basis for a gender-specific personalized …

Although alcohol use disorders rank among the leading public health problems worldwide,
hazardous drinking practices and associated morbidity continue to remain underdiagnosed …

Alcoholism ranks as one of the main current threats to the health and safety of people in
most Western countries. Therefore, a high priority should be given to aims at reducing its …

Alcohol and alcohol-related diseases have become a major cause of death in Western
countries. The most sensitive and specific of the commonly used biomarkers of alcohol …

Background: Although both ethanol consumption and overweight alter the activities of
hepatic enzymes in circulation, the differentiation of an alcohol or nonalcohol basis for such …

Alcohol abuse is a major cause of abnormal liver function throughout the world. While
measurements of liver enzyme activities (GGT, ALT, AST) are important screening tools for …

Aims: Although a wide variety of biomarkers reflecting liver status are known to be
influenced by excessive ethanol consumption, the dose–response relationships between …