Epilepsy in adults

RD Thijs, R Surges, TJ O'Brien, JW Sander - The lancet, 2019 - thelancet.com
Epilepsy is one of the most common serious brain conditions, affecting over 70 million
people worldwide. Its incidence has a bimodal distribution with the highest risk in infants and …

Epilepsy surgery in children and adults

P Ryvlin, JH Cross, S Rheims - The Lancet Neurology, 2014 - thelancet.com
Epilepsy surgery is the most effective way to control seizures in patients with drug-resistant
focal epilepsy, often leading to improvements in cognition, behaviour, and quality of life …

Epilepsy: new advances

SL Moshé, E Perucca, P Ryvlin, T Tomson - The Lancet, 2015 - thelancet.com
Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …

The management of epilepsy in children and adults

P Perucca, IE Scheffer, M Kiley - Medical Journal of Australia, 2018 - Wiley Online Library
Summary The International League Against Epilepsy has recently published a new
classification of epileptic seizures and epilepsies to reflect the major scientific advances in …

Getting the best outcomes from epilepsy surgery

VN Vakharia, JS Duncan, JA Witt, CE Elger… - Annals of …, 2018 - Wiley Online Library
Neurosurgery is an underutilized treatment that can potentially cure drug‐refractory
epilepsy. Careful, multidisciplinary presurgical evaluation is vital for selecting patients and to …

Recent advances in epilepsy

M Manford - Journal of neurology, 2017 - Springer
This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics
and underlying mechanisms, including status epilepticus, drug and surgical treatments …

What can we do for people with drug-resistant epilepsy? The 2016 Wartenberg Lecture

J Engel Jr - Neurology, 2016 - AAN Enterprises
Treatment goals for epilepsy are no seizures, no side effects, as soon as possible, but these
goals are too often unmet. Approximately 1 million people in the United States continue to …

Rates and predictors of seizure freedom with vagus nerve stimulation for intractable epilepsy

DJ Englot, JD Rolston, CW Wright, KH Hassnain… - …, 2016 - journals.lww.com
BACKGROUND: Neuromodulation-based treatments have become increasingly important in
epilepsy treatment. Most patients with epilepsy treated with neuromodulation do not achieve …

Underutilization of epilepsy surgery: Part I: A scoping review of barriers

D Samanta, AP Ostendorf, E Willis, R Singh… - Epilepsy & Behavior, 2021 - Elsevier
One-third of persons with epilepsy have seizures despite appropriate medical therapy. Drug
resistant epilepsy (DRE) is associated with neurocognitive and psychological decline, poor …

Prevalence and incidence of drug-resistant mesial temporal lobe epilepsy in the United States

AA Asadi-Pooya, GR Stewart, DJ Abrams, A Sharan - World neurosurgery, 2017 - Elsevier
Objective We reviewed data on the epidemiology of epilepsy in the United States and
estimated the prevalence and incidence of drug-resistant temporal lobe epilepsy (TLE) due …