RAD54L2-mediated DNA damage avoidance pathway specifically preserves genome integrity in response to topoisomerase 2 poisons
Type II topoisomerases (TOP2) form transient TOP2 cleavage complexes (TOP2ccs) during
their catalytic cycle to relieve topological stress. TOP2ccs are covalently linked TOP2-DNA …
their catalytic cycle to relieve topological stress. TOP2ccs are covalently linked TOP2-DNA …
ISW1a modulates cohesin distribution in centromeric and pericentromeric regions
I Litwin, M Nowicka, K Markowska… - Nucleic Acids …, 2023 - academic.oup.com
Cohesin is a highly conserved, multiprotein complex whose canonical function is to hold
sister chromatids together to ensure accurate chromosome segregation. Cohesin …
sister chromatids together to ensure accurate chromosome segregation. Cohesin …
Replication stress response in fission yeast differentially depends on maintaining proper levels of Srs2 helicase and Rrp1, Rrp2 DNA translocases
G Baranowska, D Misiorna, W Białek, K Kramarz… - PLOS …, 2024 - journals.plos.org
Homologous recombination is a key process that governs the stability of eukaryotic
genomes during DNA replication and repair. Multiple auxiliary factors regulate the choice of …
genomes during DNA replication and repair. Multiple auxiliary factors regulate the choice of …