Alcoholic neuropathy emerges following the persistent alcohol imbibing, and triggers nerve
damage through de-escalating the receptors situated in the central nervous system (CNS) …

Chronic widespread pain, such as observed in irritable bowel (IBS) and fibromyalgia (FMS)
syndrome, are markedly affected by stress. While such forms of stress-induced hyperalgesia …

Epinephrine produces sexually dimorphic β2‐adrenergic receptor‐mediated mechanical
hyperalgesia, with male rats exhibiting greater hyperalgesia. Because female rats have …

To explore the relationship between psychological stress and masticatory muscle pain, we
created a communication stress animal model to determine whether psychological stress …

Although clinical studies support the suggestion that stress is a risk factor for painful
chemotherapy-induced peripheral neuropathy (CIPN), there is little scientific validation to …

Although mechanical hyperalgesia associated with medical procedures is the major source
of severe pain in burn-injured patients, little is known about its underlying mechanism. One …

Objectives: To review recent studies on the etiopathogenetic role and clinical relevance of
life stress in medically unexplained syndromes characterized by chronic widespread …

Chronic muscle pain remains a significant source of suffering and disability despite the
adoption of pharmacologic and physical therapies. Muscle pain is mediated by free nerve …

Duloxetine, a serotonin and norepinephrine reuptake inhibitor, is the best-established
treatment for painful chemotherapy-induced peripheral neuropathy (CIPN). While it is only …

In studies of the role of primary afferent nociceptor plasticity in the transition from acute to
chronic pain we recently reported that exposure to unpredictable sound stress or a prior …