Searching new antifungals: The use of in vitro and in vivo methods for evaluation of natural compounds
L Scorzoni, F Sangalli-Leite… - Journal of …, 2016 - Elsevier
In the last decades, the increased number of immunocompromised patients has led to the
emergence of many forms of fungal infections. Furthermore, there are a restricted arsenal of …
emergence of many forms of fungal infections. Furthermore, there are a restricted arsenal of …
Antimicrobial Activity of Heterotrophic Bacterial Communities from the Marine Sponge Erylus discophorus (Astrophorida, Geodiidae)
Heterotrophic bacteria associated with two specimens of the marine sponge Erylus
discophorus were screened for their capacity to produce bioactive compounds against a …
discophorus were screened for their capacity to produce bioactive compounds against a …
Dectin-2-targeted antifungal liposomes exhibit enhanced efficacy
Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus cause life-
threatening candidiasis, cryptococcosis, and aspergillosis, resulting in several hundred …
threatening candidiasis, cryptococcosis, and aspergillosis, resulting in several hundred …
β-cyclodextrin polymer/Soluplus® encapsulated Ebselen ternary complex (EβpolySol) as a potential therapy for vaginal candidiasis and pre-exposure prophylactic for …
Epidemiological findings have discussed recurrent and persistent vulvovaginal candidiasis
to be a major manifestation of HIV infected women. Conversely, women with vulvovaginal …
to be a major manifestation of HIV infected women. Conversely, women with vulvovaginal …
Bioactivities of nano-scale magnesium oxide prepared using aqueous extract of Moringa oleifera leaves as green agent
In this research, nano-size MgO (NS-MgO) was prepared from MgCl 2 solution using
aqueous extract of Moringa oleifera leaves (AEMOL) as green agent. Preparation procedure …
aqueous extract of Moringa oleifera leaves (AEMOL) as green agent. Preparation procedure …
Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library
DJM Cruz, RM Bonotto, RGB Gomes… - PLoS neglected …, 2013 - journals.plos.org
Chikungunya virus (CHIKV) is a mosquito-borne arthrogenic alphavirus that causes acute
febrile illness in humans accompanied by joint pains and in many cases, persistent …
febrile illness in humans accompanied by joint pains and in many cases, persistent …
Fungal endophytes from arid areas of Andalusia: high potential sources for antifungal and antitumoral agents
V González-Menéndez, G Crespo, N De Pedro… - Scientific reports, 2018 - nature.com
Native plant communities from arid areas present distinctive characteristics to survive in
extreme conditions. The large number of poorly studied endemic plants represents a unique …
extreme conditions. The large number of poorly studied endemic plants represents a unique …
Bioactivities and Extract Dereplication of Actinomycetales Isolated From Marine Sponges
In the beginning of the twenty-first century, humanity faces great challenges regarding
diseases and health-related quality of life. A drastic rise in bacterial antibiotic resistance, in …
diseases and health-related quality of life. A drastic rise in bacterial antibiotic resistance, in …
Deciphering Staphylococcus xylosus and Staphylococcus equorum mode of action against Penicillium nordicum in a dry-cured ham model system
Penicillium nordicum is one of the major producers of ochratoxin A (OTA) in dry-cured ham.
Staphylococcus xylosus Sx8 and Staphylococcus equorum Se31 have been previously …
Staphylococcus xylosus Sx8 and Staphylococcus equorum Se31 have been previously …
The spatial organization of sphingofungin biosynthesis in Aspergillus fumigatus and its cross-interaction with sphingolipid metabolism
K Jojić, F Gherlone, Z Cseresnyés, AU Bissell… - Mbio, 2024 - Am Soc Microbiol
Sphingofungins are sphinganine analog mycotoxins acting as inhibitors of serine palmitoyl
transferases, enzymes responsible for the first step in the sphingolipid biosynthesis …
transferases, enzymes responsible for the first step in the sphingolipid biosynthesis …